eravacycline
National Institutes of Health
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Abstract Background Orthopedic foreign body-associated infection can be difficult to treat due to the formation of biofilms…
Eravacycline (7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline or TP-434) is a novel, fully synthetic broad…
A convergent route to eravacycline (1) has been developed by employing Michael-Dieckmann cyclization between enone 3 and a fully…
Abstract Background Eravacycline (ERV) is a fluorocycline being developed for the treatment of serious infections, including…
P olymyxin antibiotics are considered a last line of defense in the treatment of severe infections caused by multidrug-resistant…
Purpose of review The progressive increase of respiratory tract infections caused by multidrug-resistant organisms (MDROs) has…
Gram-negative bacteria are common causes of intra-abdominal infections and urinary tract infections, and resistance amongst these…
ABSTRACT Eravacycline is a novel broad-spectrum fluorocycline with potent Gram-negative activity, including for multidrug…
After some years of stagnation there have been several new successful developments in the field of antibacterial agents. Most of…