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epicillin

Known as: 6-(D-2-amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, dihydroampicillin 
An extended-spectrum, semisynthetic aminopenicillin with antibacterial activity. Epicillin binds to and inactivates penicillin-binding proteins (PBPs… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

AmpicillinAnti-Bacterial Agents

Narrower (2)

DexacillinSpectacillin
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
Reversed-phase high-performance liquid chromatographic assay methods for the analysis of a range of penicillins in in vitro permeation studies.
1979
1979
Comparative activities of ampicillin, epicillin and amoxycillin in vitro and in vivo.
The antibacterial activities of three aminopenicillins ampicillin, epicillin and amoxycillin were compared in vitro and in vivo… 
1979
1979
The effect of three frequently applied antibiotics on the colonization resistance of the digestive tract of mice
SUMMARY The influence of treatment with increasing oral doses of three absorbable antibiotics on the colonization resistance of… 
Highly Cited
1978
Highly Cited
1978
Physicochemical properties of amphoteric beta-lactam antibiotics I: Stability, solubility, and dissolution behavior of amino penicillins as a function of pH.
The degradation rate, solubility, and dissolution rate of amino penicillins, amoxicillin, ampicillin, epicillin, and cyclacillin… 
1978
1978
Cephradine and epicillin in body fluids of lactating and pregnant women.
The passage of two antibiotics, cephradine and epicillin, into the milk of 12 lactating women and the amniotic fluid of 48… 
1976
1976
Susceptibility of Ampicillin-Resistant Haemophilus influenzae to Seven Penicillins
Sixty-seven clinical isolates of Haemophilus influenzae from various sections of the United States, England, and Germany were… 
1975
1975
Sequence Effect on Ampicillin Blood Levels Noted in an Amoxicillin, Ampicillin, and Epicillin Triple Crossover Study
Amoxicillin, ampicillin, and epicillin (500 mg of each) were given orally to fasting men and women in a triple crossover study… 
1973
1973
Separation of penicillins of closely related structure by partition chromatography on paper and cellulose thin-layer plates.
1971
1971
Epicillin: Experimental Chemotherapy, Pharmacodynamics, and Susceptibility Testing
Epicillin exhibits excellent therapeutic activity when administered orally or subcutaneously to mice infected with a variety of… 
1971
1971
Epicillin: In Vitro Laboratory Studies
A new semisynthetic penicillin, structurally related to ampicillin, has been assigned the generic name epicillin, 6-[d-2-amino-2… 
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