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eosinophil degranulation

Known as: eosinophil granule exocytosis 
The regulated exocytosis of secretory granules containing preformed mediators such as major basic protein, eosinophil peroxidase, and eosinophil… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Nonpathogenic, Environmental Fungi Induce Activation and Degranulation of Human Eosinophils1
Eosinophils and their products are probably important in the pathophysiology of allergic diseases, such as bronchial asthma, and… 
Highly Cited
2001
Highly Cited
2001
Selective modulation of chemokinesis, degranulation, and apoptosis in eosinophils through the PGD2 receptors CRTH2 and DP.
BACKGROUND PGD(2) is the major prostanoid released by mast cells during an allergic response. Its role in the allergic response… 
Highly Cited
2000
Highly Cited
2000
The Effect of IL-5 and Eotaxin Expression in the Lung on Eosinophil Trafficking and Degranulation and the Induction of Bronchial Hyperreactivity1
The mechanisms regulating the selective migration and degranulation of eosinophils in the asthmatic lung and the subsequent… 
Highly Cited
1999
Highly Cited
1999
Adenosine A3 receptors on human eosinophils mediate inhibition of degranulation and superoxide anion release
The role of adenosine A3 receptors on human eosinophil degranulation and superoxide anion (O2−) release was studied in vitro… 
Highly Cited
1995
Highly Cited
1995
Allergen-specific IgG1 and IgG3 through Fc gamma RII induce eosinophil degranulation.
Evidence suggests that eosinophils contribute to inflammation in bronchial asthma by releasing chemical mediators and cytotoxic… 
Highly Cited
1994
Highly Cited
1994
CD11b/CD18 (Mac-1) is required for degranulation of human eosinophils induced by human recombinant granulocyte-macrophage colony-stimulating factor and platelet-activating factor.
Recent evidence suggests adhesion molecules play an important role in the function of leukocytes. Because human eosinophils are… 
Highly Cited
1992
Highly Cited
1992
Tissue eosinophilia and eosinophil degranulation in syndromes associated with fibrosis.
Eosinophilia has long been associated with endomyocardial fibrosis, but the involvement of the eosinophilia in fibrosis of other… 
Highly Cited
1990
Highly Cited
1990
Regulatory effect of cytokines on eosinophil degranulation.
We tested the effects of different cytokines on IgA- and IgG-induced eosinophil degranulation in vitro to determine the potential… 
Highly Cited
1985
Highly Cited
1985
Ultrastructural characterization and morphometric analysis of human eosinophil degranulation.
Human eosinophil degranulation induced by the calcium ionophore A23187 was examined by transmission and scanning electron… 
Highly Cited
1984
Highly Cited
1984
Mechanisms for eosinophil degranulation; release of the eosinophil cationic protein.
Mechanisms for degranulation in human eosinophils were evaluated. Release of eosinophil cationic protein (ECP), a unique… 
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