enoyl-CoA hydratase activity

Known as: enol-CoA hydratase activity, 2-octenoyl coenzyme A hydrase activity, enoyl hydrase activity 
Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2-enoyl-CoA + H2O. [EC:4.2.1.17]
National Institutes of Health

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AUH protein, human

Papers overview

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2015
2015
Elimination of hydrogenase active site assembly blocks H2 production and increases ethanol yield in Clostridium thermocellum
BACKGROUND The native ability of Clostridium thermocellum to rapidly consume cellulose and produce ethanol makes it a leading… (More)
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Highly Cited
2012
Highly Cited
2012
Lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-taxane-based chemotherapy (GeparQuinto, GBG 44): a randomised phase 3 trial.
BACKGROUND We compared the efficacy and safety of the addition of lapatinib versus trastuzumab to anthracycline-taxane-based… (More)
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Highly Cited
2012
Highly Cited
2012
Mechanisms of Oxidative Damage in Multiple Sclerosis and Neurodegenerative Diseases: Therapeutic Modulation via Fumaric Acid Esters
Oxidative stress plays a crucial role in many neurodegenerative conditions such as Alzheimer's disease, amyotrophic lateral… (More)
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2011
2011
Conserved Arabidopsis ECHIDNA protein mediates trans-Golgi-network trafficking and cell elongation.
Multiple steps of plant growth and development rely on rapid cell elongation during which secretory and endocytic trafficking via… (More)
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2009
Highly Cited
2009
Journal of Statistical Mechanics : Theory and Experiment Univariate and multivariate properties of wind velocity time series
We analyze the time series of hourly average wind speeds measured at 29 different stations located in Sicily, a region with a… (More)
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Highly Cited
2006
Highly Cited
2006
Mechanism of action of sulforaphane: inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human…
Exposure of sulforaphane to HepG2 cells increased heme oxygenase-1 (HO-1) expression by activating antioxidant response element… (More)
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2006
2006
Ebselen, a seleno-organic antioxidant, as an electrophile.
Ebselen [2-phenyl-1,2-benzisoselenazol-3(2H)-one], a seleno-organic compound showing glutathione peroxidase-like activity, is one… (More)
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2002
2002
Structural mechanism of enoyl-CoA hydratase: three atoms from a single water are added in either an E1cb stepwise or concerted fashion.
We have determined the crystal structure of the enzyme enoyl-CoA hydratase (ECH) from rat liver with the bound substrate 4-(N,N… (More)
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Highly Cited
2002
Highly Cited
2002
Genetic analysis of the archaeon Methanosarcina barkeri Fusaro reveals a central role for Ech hydrogenase and ferredoxin in methanogenesis and carbon fixation.
Ech hydrogenase (Ech) from the methanogenic archaeon Methanosarcina barkeri catalyzes the reversible reduction of ferredoxin by H… (More)
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1995
1995
Enoyl-CoA hydratase and isomerase form a superfamily with a common active-site glutamate residue.
Mitochondrial 2-enoyl-CoA hydratase (mECH) and 3,2-trans-enoyl-CoA isomerase (mECI), two enzymes which catalyze totally different… (More)
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