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endomorphin 1

Known as: Tyr-Pro-Trp-Phe-Nh2, endomorphin-1, tyrosyl-prolyl-tryptophyl-phenylalaninamide 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Analgesics, OpioidOligopeptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
The Endomorphin System and Its Evolving Neurophysiological Role
Endomorphin-1 (Tyr-Pro-Trp-Phe-NH2) and endomorphin-2 (Tyr-Pro-Phe-Phe-NH2) are two endogenous opioid peptides with high affinity… 
Highly Cited
2000
Highly Cited
2000
Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties.
The existence of dimers and oligomers for many G protein-coupled receptors has been described by us and others. Since many G… 
Highly Cited
2000
Highly Cited
2000
Differential antinociceptive effects of endomorphin-1 and endomorphin-2 in the mouse.
Two highly selective mu-opioid receptor agonists, endomorphin-1 and endomorphin-2, have been identified and postulated to be… 
Highly Cited
2000
Highly Cited
2000
Differential cardiorespiratory effects of endomorphin 1, endomorphin 2, DAMGO, and morphine.
The novel endogenous mu-opioid receptor (MOR) agonists endomorphin 1 (EM1) and 2 (EM2) were tested for their cardiorespiratory… 
Highly Cited
1999
Highly Cited
1999
Spinal analgesic action of endomorphins in acute, inflammatory and neuropathic pain in rats.
Highly Cited
1998
Highly Cited
1998
Pharmacological characterization of endomorphin-1 and endomorphin-2 in mouse brain.
The recently isolated peptides endomorphin-1 and endomorphin-2 have been suggested to be the endogenous ligands for the mu… 
Highly Cited
1998
Highly Cited
1998
Specific G protein activation and mu-opioid receptor internalization caused by morphine, DAMGO and endomorphin I.
Highly Cited
1998
Highly Cited
1998
Endomorphins have orexigenic and anxiolytic activities in mice
THIS study was designed to investigate the effects of endomorphin 1 and 2, recently identified μ-opioid receptor selective… 
Highly Cited
1997
Highly Cited
1997
Spinal analgesic actions of the new endogenous opioid peptides endomorphin‐1 and ‐2
TWO highly-selective μ-opioid receptor agonists, endomorphin-1 and -2, were recently purified from bovine brain and are… 
Highly Cited
1997
Highly Cited
1997
Localization of Endomorphin-2-Like Immunoreactivity in the Rat Medulla and Spinal Cord
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