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endomorphin 1

Known as: Tyr-Pro-Trp-Phe-Nh2, endomorphin-1, tyrosyl-prolyl-tryptophyl-phenylalaninamide 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Analgesics, OpioidOligopeptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
The Peripheral Antinociceptive Effects of Endomorphin-1 and Kynurenic Acid in the Rat Inflamed Joint Model
BACKGROUND: Several data suggest that both opioid and N-methyl-d-aspartate (NMDA) receptors are localized at the peripheral level… 
Highly Cited
2007
Highly Cited
2007
Antidepressant-Like Effect of Endomorphin-1 and Endomorphin-2 in Mice
Endomorphin-1 (Tyr-Pro-Trp-Phe-NH2) and endomorphin-2 (Tyr-Pro-Phe-Phe-NH2) are two recently isolated μ-opioid selective peptides… 
2007
2007
Attenuation of knee joint inflammation by peripherally administered endomorphin-1
Endomorphin-1 is a selective endogenous ligand for the μ-opioid receptor, and this study investigated the effect of endomorphin-1… 
Highly Cited
2007
Highly Cited
2007
Endomorphin-1 modulates intrinsic inhibition in the dorsal vagal complex.
Mu-opioid receptor (MOR) agonists profoundly influence digestive and other autonomic functions by modulating neurons in nucleus… 
Highly Cited
2007
Highly Cited
2007
Modulation of Ca2+ channels by heterologously expressed wild-type and mutant human micro-opioid receptors (hMORs) containing the A118G single-nucleotide polymorphism.
The most common single-nucleotide polymorphism (SNP) of the human mu-opioid receptor (hMOR) gene occurs at position 118 (A118G… 
2004
2004
Internalization and down-regulation of mu opioid receptors by endomorphins and morphine in SH-SY5Y human neuroblastoma cells
Highly Cited
2001
Highly Cited
2001
MDR1 P-glycoprotein transports endogenous opioid peptides
Review
1999
Review
1999
Pain Inhibition by Endomorphins
Abstract: Spinal analgesic effects of endomorphin‐1 and endomorphin‐2 were studied during acute, inflammatory, and neuropathic… 
Highly Cited
1998
Highly Cited
1998
Endomorphins have orexigenic and anxiolytic activities in mice
THIS study was designed to investigate the effects of endomorphin 1 and 2, recently identified μ-opioid receptor selective… 
1998
1998
Endomorphins decrease heart rate and blood pressure possibly by activating vagal afferents in anesthetized rats
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