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endolysosome

An transient hybrid organelle formed by fusion of a late endosome with a lysosome, and in which active degradation takes place. [GOC:pde, PMID… 
National Institutes of Health

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endolysosome lumenendolysosome membrane

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Deimmunizing substitutions in Pseudomonas exotoxin domain III perturb antigen processing without eliminating T-cell epitopes
Effective adaptive immune responses depend on activation of CD4+ T cells via the presentation of antigen peptides in the context… 
2018
2018
Identification and characterization of arginine finger-like motifs, and endosome-lysosome basolateral sorting signals within the Coxiella burnetii type IV secreted effector protein CirA
2017
2017
A well-known potassium channel plays a critical role in lysosomes
Zhu discusses work on organeller ion transporters from Wang et al. describing the importance of a lysosomal voltage-sensitive Ca2… 
2016
2016
Identification of Toxoplasma TgPH1, a pleckstrin homology domain-containing protein that binds to the phosphoinositide PI(3,5)P2.
2016
2016
Role of Endolysosomes in Skeletal Muscle Pathology Observed in a Cholesterol-Fed Rabbit Model of Alzheimer’s Disease
Deficits in skeletal muscles contribute not only to the functional decline in people living with Alzheimer’s disease (AD), but… 
2015
2015
Hyperactivated endolysosomal trafficking in melanoma
Cutaneous melanoma is an increasingly frequent solid tumor that accounts for 80% of skin cancer-related deaths. Characterized by… 
2014
2014
Intracellular renin-angiotensin signaling: working from the inside-out in hypothalamic neurons. Focus on "Direct evidence of intracrine angiotensin II signaling in neurons".
  • R. Wondergem
  • American Journal of Physiology - Cell Physiology
  • 2014
  • Corpus ID: 12089135
the renin-angiotensin system (RAS) has been one of the most extensively studied endocrine control systems in humans. It harks… 
Highly Cited
2012
Highly Cited
2012
Vpu Mediates Depletion of Interferon Regulatory Factor 3 during HIV Infection by a Lysosome-Dependent Mechanism
ABSTRACT HIV has evolved sophisticated mechanisms to avoid restriction by intracellular innate immune defenses that otherwise… 
2011
2011
Innate immunity: TLR9 mutations reveal a new level of self tolerance
Processing-independent activation of a TLR9 mutant overcomes self tolerance. 
Review
1993
Review
1993
Antigen processing and presentation. The role of the endoplasmic reticulum.
The immune system has evolved to recognize and destroy pathogens. Invasion by extracellular microorganisms is mainly controlled… 
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