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endolysosome

An transient hybrid organelle formed by fusion of a late endosome with a lysosome, and in which active degradation takes place. [GOC:pde, PMID… Expand
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Autophagy, an important catabolic pathway implicated in a broad spectrum of human diseases, begins by forming double membrane… Expand
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2013
2013
The increased life expectancy of people living with HIV-1/AIDS is accompanied by increased prevalence of HIV-1-associated… Expand
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2012
2012
AIMS Elevated levels of circulating cholesterol are extrinsic factors contributing to the pathogenesis of sporadic Alzheimer's… Expand
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Highly Cited
2011
Highly Cited
2011
TLR3, TLR7, and TLR9 are cleaved in the same step-wise manner in all immune cell types examined. 
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Highly Cited
2009
Highly Cited
2009
The mechanisms by which receptors guide intracellular virus transport are poorly characterized. The murine polyomavirus (Py… Expand
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Highly Cited
2009
Highly Cited
2009
Chitosan was functionalized with imidazole moieties (CHimi) with the aim of improving its buffering capacity and promoting the… Expand
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Highly Cited
2008
Highly Cited
2008
Mammalian Toll-like receptors (TLRs) 3, 7, 8 and 9 initiate immune responses to infection by recognizing microbial nucleic acids… Expand
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Highly Cited
2006
Highly Cited
2006
Carrier-mediated delivery of drugs into the cytosol is often limited by either release from the carrier or release from an… Expand
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Highly Cited
2000
Highly Cited
2000
Poly(ethylenimine) (PEI) is a synthetic polycation that has been used successfully for gene delivery both in vitro and in vivo… Expand
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Highly Cited
1999
Highly Cited
1999
Interleukin 1beta (IL-1beta), a secretory protein lacking a signal peptide, does not follow the classical endoplasmic reticulum… Expand
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