endolysosome

An transient hybrid organelle formed by fusion of a late endosome with a lysosome, and in which active degradation takes place. [GOC:pde, PMID… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2018
051019882018

Papers overview

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Highly Cited
2015
Highly Cited
2015
Autophagy, an important catabolic pathway implicated in a broad spectrum of human diseases, begins by forming double membrane… (More)
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2013
2013
The increased life expectancy of people living with HIV-1/AIDS is accompanied by increased prevalence of HIV-1-associated… (More)
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2012
2012
Combined anti-retroviral therapeutic drugs effectively increase the lifespan of HIV-1-infected individuals who then have a higher… (More)
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2012
2012
AIMS Elevated levels of circulating cholesterol are extrinsic factors contributing to the pathogenesis of sporadic Alzheimer's… (More)
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Highly Cited
2011
Highly Cited
2011
Toll-like receptor (TLR) 9 requires proteolytic processing in the endolysosome to initiate signaling in response to DNA. However… (More)
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Highly Cited
2010
Highly Cited
2010
Membrane fusion and fission events in intracellular trafficking are controlled by both intraluminal Ca(2+) release and… (More)
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2010
2010
Alzheimer's disease (AD) is characterized clinically by progressive disturbances in memory, judgment, reasoning, and olfaction… (More)
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2009
2009
The mechanisms by which receptors guide intracellular virus transport are poorly characterized. The murine polyomavirus (Py… (More)
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Highly Cited
2008
Highly Cited
2008
Mammalian Toll-like receptors (TLRs) 3, 7, 8 and 9 initiate immune responses to infection by recognizing microbial nucleic acids… (More)
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Highly Cited
1999
Highly Cited
1999
Interleukin 1beta (IL-1beta), a secretory protein lacking a signal peptide, does not follow the classical endoplasmic reticulum… (More)
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