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elvitegravir

Known as: elvitégravir, 6-(3-chloro-2-fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, 6-(3-Chloro-2-fluorobenzyl)-1-((2S)-1-hydroxy-3-methylbutan-2-yl)-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid 
A modified quinolone antibiotic with activity against human immunodeficiency virus 1. Elvitegravir is an inhibitor of viral integrase and retains… 
National Institutes of Health

Related topics

Related topics

7 relations

Narrower (4)

GS 9137GenvoyaStribildVitekta
HIV InfectionsHIV Integrase Inhibitors [MoA]

Broader (1)

JTK 303

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Selective resistance profiles emerging in patient-derived clinical isolates with cabotegravir, bictegravir, dolutegravir, and elvitegravir
Integrase strand transfer inhibitors (INSTIs) are recommended for first-line HIV therapy based on their relatively high genetic… 
Review
2009
Review
2009
Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors
Merck's MK-0518, known as raltegravir, has recently become the first FDA-approved HIV-1 integrase (IN) inhibitor and has since… 
Highly Cited
2008
Highly Cited
2008
Resistance Mutations in Human Immunodeficiency Virus Type 1 Integrase Selected with Elvitegravir Confer Reduced Susceptibility to a Wide Range of Integrase Inhibitors
ABSTRACT Integration of viral DNA into the host chromosome is an essential step in the life cycle of retroviruses and is… 
Highly Cited
2007
Highly Cited
2007
Broad Antiretroviral Activity and Resistance Profile of the Novel Human Immunodeficiency Virus Integrase Inhibitor Elvitegravir (JTK-303/GS-9137)
ABSTRACT Integrase (IN), an essential enzyme of human immunodeficiency virus (HIV), is an attractive antiretroviral drug target… 
Highly Cited
2005
Highly Cited
2005
Blood flow and structure interactions in a stented abdominal aortic aneurysm model.
Highly Cited
2005
Highly Cited
2005
Fluid-structure interaction effects on sac-blood pressure and wall stress in a stented aneurysm.
An aneurysm is a local artery ballooning greater than 50% of its nominal diameter with a risk of sudden rupture. Minimally… 
Highly Cited
2004
Highly Cited
2004
A deletion affecting several gene candidates is present in the Evergrowing peach mutant.
Evergrowing (EVG) peach is one of only two described mutants affecting winter dormancy in woody perennial species. EVG peach does… 
Review
2001
Review
2001
Human vomeronasal organ function: a critical review of best and worst cases.
The human vomeronasal organ (VNO) has been the subject of some interest in the scientific literature and of considerable… 
Highly Cited
1997
Highly Cited
1997
The intermediate layer: a morphologic study of the elastin and hyaluronic acid constituents of normal human vocal folds.
Highly Cited
1996
Highly Cited
1996
Angiogenesis in abdominal aortic aneurysms.
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