elvitegravir

Known as: elvitégravir, 6-(3-chloro-2-fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, 6-(3-Chloro-2-fluorobenzyl)-1-((2S)-1-hydroxy-3-methylbutan-2-yl)-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid 
A modified quinolone antibiotic with activity against human immunodeficiency virus 1. Elvitegravir is an inhibitor of viral integrase and retains… (More)

Topic mentions per year

Topic mentions per year

1961-2018
05019612018

Papers overview

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Highly Cited
2014
Highly Cited
2014
This July 2014 edition of the IAS–USA drug resistance mutations list updates the figures last published in March 2013.1 The… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND The integrase inhibitor elvitegravir (EVG) has been co-formulated with the CYP3A4 inhibitor cobicistat (COBI… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND The HIV integrase strand transfer inhibitor elvitegravir (EVG) has been co-formulated with the CYP3A4 inhibitor… (More)
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2011
2011
OBJECTIVE In this study, we characterized elvitegravir activity in the context of raltegravir resistance mutations. DESIGN… (More)
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2009
2009
Mapping and sequencing of the non-dormant evg mutant in peach [Prunus persica (L.) Batsch] identified six tandem-arrayed DAM… (More)
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Highly Cited
2008
Highly Cited
2008
Integrase (IN), an essential enzyme of human immunodeficiency virus (HIV), is an attractive antiretroviral drug target. The… (More)
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Highly Cited
2008
Highly Cited
2008
Integration of viral DNA into the host chromosome is an essential step in the life cycle of retroviruses and is facilitated by… (More)
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2008
2008
OBJECTIVES We investigated the in vitro phenotypic susceptibility of HIV-2 isolates from integrase inhibitor (INI)-naive patients… (More)
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2005
2005
An aneurysm is a local artery ballooning greater than 50% of its nominal diameter with a risk of sudden rupture. Minimally… (More)
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Highly Cited
2002
Highly Cited
2002
Many plants use day length as an environmental cue to ensure proper timing of the switch from vegetative to reproductive growth… (More)
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