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GS 9137

Known as: GS-9137, GS9137 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

JTK 303elvitegravir

Papers overview

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2012
2012
Design, Practical Synthesis, and Biological Evaluation of Novel 6-(Pyrazolylmethyl)-4-quinoline-3-carboxylic Acid Derivatives as HIV-1 Integrase Inhibitors
A series of novel 6-(pyrazolylmethyl)-4-oxo-4H-quinoline-3-carboxylic acid derivatives bearing different substituents on the N… 
Review
2010
Review
2010
Development of integrase inhibitors of quinolone acid derivatives for treatment of AIDS: an overview.
HIV-1 integrase (IN), which has no cellular counterpart, has been intensely studied over the past 15 years and has been fully… 
2008
2008
Genetic diversity of integrase (IN) sequences in antiretroviral treatment-naive and treatment-experienced HIV type 2 patients.
Two potent integrase inhibitors (IN-Is), raltegravir (RAL, MK-0518) and elvitegravir (EGV, GS-9137), have been shown to be potent… 
Review
2008
Review
2008
Anti-infectives: clinical progress of HIV-1 integrase inhibitors.
BACKGROUND HIV-1 integrase (IN) represents a therapeutically advantageous viral target to treat HIV/AIDS in the clinic. Over a… 
Highly Cited
2007
Highly Cited
2007
Pharmacokinetics of Emtricitabine, Tenofovir, and GS-9137 Following Coadministration of Emtricitabine/Tenofovir Disoproxil Fumarate and Ritonavir-Boosted GS-9137
Objectives:To evaluate the potential for clinically relevant drug-drug interaction between emtricitabine/tenofovir disoproxil… 
2006
2006
GS-9137 : Anti-HIV agent HIV integrase inhibitor
Significant advances have been made in the development of HIV-1 reverse transcriptase and protease inhibitors for the treatment… 
2006
2006
MK-0518 and GS-9137: two promising integrase inhibitors in the pipeline.
Possibly the most exciting news to come out of the 13th Conference on Retroviruses and Opportunistic Infections, held in Denver… 
2006
2006
Snapshots for May 2006
s (91, 92, 293). A European group (abstract 33LB) demonstrated in the first randomized controlled trial that active herpes… 
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