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elliptinium acetate

Known as: ellipticinium acetate, 2-methyl-9-hydroxyellipticinium acetate, 9-Hydroxy-2-methylellipticinium acetate 
Acetate salt of elliptinium, a derivative of the alkaloid ellipticine isolated from species of the plant family Apocynaceae, including Bleekeria… 
National Institutes of Health

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2 relations

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Celiptium

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elliptinium

Papers overview

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2004
2004
In vitro cytotoxicity of S16020-2, a new olivacine derivative
SummaryS16020-2 is a new olivacine derivative which has recently shown a marked antitumor activity in various experimental models… 
1986
1986
Covalent binding of elliptinium acetate (NSC 264137) to nucleic acids of L1210 cells in culture.
Elliptinium acetate (9-OH-NME; Celiptium) is an antineoplastic agent currently used in the treatment of metastatic breast cancer… 
1986
1986
Ribose as the preferential target for the oxidized form of elliptinium acetate in ribonucleos(t)ides. Biological activities of the resulting adducts.
The covalent binding of the oxidized form of elliptinium acetate, an antitumor drug, to various ribonucleos(t)ides is described… 
1985
1985
Drug-induced antibodies during 2-N-methyl-9-hydroxyellipticinium acetate (NSC-264137) treatment: schedule dependency and relationship to hemolysis.
Drug-dependent antibodies were investigated in patients treated with elliptinium acetate, a cytostatic drug with activity in… 
1984
1984
Covalent binding of the antitumor agent N2-methyl-9-hydroxy-ellipticinium acetate (NSC 264137) on RNA and poly A in vitro.
1984
1984
Ellipticine derivatives interacting with model membranes. Influence of quaternarization of nitrogen-2.
1984
1984
Regioselective arylation of ribose in adenosine and guanosine with the antitumor drug N2-methyl-9-hydroxyellipticinium acetate.
The transformation of the antitumor drug N2-methyl-9-hydroxy-ellipticinium by a peroxidase-hydrogen peroxide system, which has… 
1982
1982
Phase I clinical study of 9-hydroxy-2N-methyl-ellipticinium acetate (NSC-264137) administered on a 5-day i.v. schedule.
1980
1980
Metabolism and disposition studies of 9-hydroxyellipticine and 2-methyl-9-hydroxyellipticinium acetate in animals.
Radiolabeled 9-hydroxyellipticine (iv and ip routes) and the corresponding radioactive quaternary salt, 2-methyl-9… 
1978
1978
Some antitumor derivatives of ellipticine deprived of mutagenic properties.
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