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elliptinium acetate

Known as: ellipticinium acetate, 2-methyl-9-hydroxyellipticinium acetate, 9-Hydroxy-2-methylellipticinium acetate 
Acetate salt of elliptinium, a derivative of the alkaloid ellipticine isolated from species of the plant family Apocynaceae, including Bleekeria… Expand
National Institutes of Health

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2004
2004
SummaryS16020-2 is a new olivacine derivative which has recently shown a marked antitumor activity in various experimental models… Expand
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Review
1997
Review
1997
The nuclear enzymes DNA topoisomerases I and II appeared as cellular targets for several antitumor drugs: campthotecin… Expand
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1993
1993
Significant low density lipoprotein (LDL) uptake by tumour cells led to the use of LDL as a discriminatory vehicle for the… Expand
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1993
1993
Elliptinium acetate (Celiptium) is an intercalating agent belonging to the ellipticine family. This agent has demonstrated… Expand
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1992
1992
Circular dichroism was applied to the analysis of drug-DNA associations. With the octanucleotide d(TGACGTCA) (octanucleotide I… Expand
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1990
1990
Thirty-five patients with metastatic breast cancer who had received one or two prior chemotherapeutic regimens were treated with… Expand
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Highly Cited
1990
Highly Cited
1990
Forty-nine patients with metastatic nonanaplastic thyroid carcinoma were treated over a 10-year period. Five successive… Expand
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1990
1990
Numerous antitumor and antibacterial agents inhibit type II DNA topoisomerases, yielding, in each case, a complex of enzyme… Expand
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1983
1983
Uptake of two ellipticine derivatives, 2-N-methyl-ellipticinium (NME) and 2-N-methyl-9-hydroxy-ellipticinium, by sensitive and… Expand
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1978
1978
Abstract Ellipticine (5,11 -dimethyl-6-H-pyrido[4-3b]carbazole) and its derivatives bind strongly to the oxidized and reduced… Expand
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