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elliptinium acetate

Known as: ellipticinium acetate, 2-methyl-9-hydroxyellipticinium acetate, 9-Hydroxy-2-methylellipticinium acetate 
Acetate salt of elliptinium, a derivative of the alkaloid ellipticine isolated from species of the plant family Apocynaceae, including Bleekeria… Expand
National Institutes of Health

Papers overview

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1993
1993
Significant low density lipoprotein (LDL) uptake by tumour cells led to the use of LDL as a discriminatory vehicle for the… Expand
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Highly Cited
1992
Highly Cited
1992
Circular dichroism was applied to the analysis of drug-DNA associations. With the octanucleotide d(TGACGTCA) (octanucleotide I… Expand
1990
1990
Thirty-five patients with metastatic breast cancer who had received one or two prior chemotherapeutic regimens were treated with… Expand
1990
1990
Numerous antitumor and antibacterial agents inhibit type II DNA topoisomerases, yielding, in each case, a complex of enzyme… Expand
1986
1986
Elliptinium acetate (9-OH-NME; Celiptium) is an antineoplastic agent currently used in the treatment of metastatic breast cancer… Expand
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1984
1984
Four compounds of the ellipticine family were examined in their interaction with liposomes and with an isolated bacterial… Expand
1984
1984
Two metabolites of the antitumor drug N-2-methyl-9-hydroxyellipticinium acetate (Celiptium) were isolated from bile of 10 mg/kg… Expand
1983
1983
Uptake of two ellipticine derivatives, 2-N-methyl-ellipticinium (NME) and 2-N-methyl-9-hydroxy-ellipticinium, by sensitive and… Expand
Highly Cited
1978
Highly Cited
1978
Abstract Ellipticine (5,11 -dimethyl-6-H-pyrido[4-3b]carbazole) and its derivatives bind strongly to the oxidized and reduced… Expand
1978
1978
Seven derivatives of the antitumor alkaloid ellipticine were assayed for activity against murine leukaemia L1210 and for… Expand