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eliglustat

Known as: N-((1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(pyrrolidin-1-ylmethyl)ethyl)octanamide, N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-pyrrolidinyl)-2-propanyl]octanamide 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (2)

Enzyme InhibitorsPyrrolidines

Narrower (2)

Genz-112638eliglustat tartrate
eliglustat 84 MG Oral Capsuleeliglustat 84 MG Oral Capsule [Cerdelga]

Papers overview

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2020
2020
Effect of eliglustat on the pharmacokinetics of digoxin, metoprolol, and oral contraceptives and absorption of eliglustat when coadministered with acid-reducing agents.
2018
2018
Process for preparation of eliglustat hemitartrate and intermediates thereof
2017
2017
Type 1 Gaucher disease (CYP2D6-eliglustat).
2015
2015
Carcinogenicity testing of eliglustat in mice and rats.
2015
2015
Entwicklung von Orphan Drugs
ZusammenfassungErkrankungen, die bei weniger als 5 von 10.000 Einwohnern auftreten, werden in Europa als „seltene Erkrankungen… 
Review
2014
Review
2014
Pedigree analysis in patients with Fabry disease: evaluating changes in referral and diagnosis over successive generations
2014
2014
EDGE: A Phase 3 study evaluating once versus twice daily dosing of eliglustat in patients with Gaucher disease type 1: interim results from the lead-in-period
2013
2013
ENCORE: A randomized, controlled, open-label non-inferiority study comparing eliglustat to imiglucerase in Gaucher disease type 1 patients on enzyme replacement therapy who have reached therapeutic…
2013
2013
Carcinogenicity testing of eliglustat in the mouse and rat
2012
2012
Eliglustat, an Investigational Oral Therapy for Gaucher Disease Type 1: Phase 2 Results After 4 Years of Treatment
Abstract 1038 Introduction: In Gaucher disease type 1 (GD1), genetically caused deficiency of the enzyme acid β-glucosidase… 
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