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ecgonine methyl ester

Known as: methyl ecgonine 
 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
AbstractA validated method based on solid-phase extraction (SPE) and liquid chromatography–ion trap tandem mass spectrometry (LC… Expand
Highly Cited
2000
Highly Cited
2000
In vitro selection of oligonucleotides has made possible the isolation of aptamers with high binding affinity for small molecules… Expand
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Highly Cited
1992
Highly Cited
1992
Twenty hair samples obtained from Bolivian mine workers who chewed 3-8 g of coca leaves daily for several years were analyzed for… Expand
Highly Cited
1989
Highly Cited
1989
The disposition of radiolabeled cocaine in humans has been studied after three routes of administration: iv injection, nasal… Expand
Highly Cited
1988
Highly Cited
1988
A rapid, sensitive, reliable quantitative GC/MS method using 0.2 mL of urine was developed for the confirmation of cocaine use… Expand
Highly Cited
1988
Highly Cited
1988
The excretion kinetics of cocaine (C) and its two major metabolites, benzoylecgonine (BZ) and ecgonine methyl ester (EME), were… Expand
Highly Cited
1984
Highly Cited
1984
In this study, cocaine, benzoylecgonine, and ecgonine methyl ester excretion in urine was measured after intravenous and… Expand
Highly Cited
1982
Highly Cited
1982
Most assays for the identification of cocaine use are aimed at detection of benzoylecgonine, a major urinary metabolite. Gas… Expand
Highly Cited
1979
Highly Cited
1979
The hydrolysis of cocaine and its N‐demethylated product, norcocaine, by esterases was examined in liver and serum. Both liver… Expand
Highly Cited
1977
Highly Cited
1977
Abstract Hydrolysis of cocaine to ecgonine methyl ester in human plasma is mediated by cholinesterase. Cocaine hydrolysis by… Expand