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ebericol

Known as: 24-methylenelanost-8-en-3 beta-ol, euphorbol, 24-methylene-24,25-dihydrolanosterol 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Background: The fungus Aspergillus fumigatus causes human diseases that are treated with CYP51 azole inhibitors. Results: We… Expand
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Highly Cited
2013
Highly Cited
2013
CYP51 encodes the cytochrome P450 sterol 14α-demethylase, an enzyme essential for sterol biosynthesis and the target of azole… Expand
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Highly Cited
2010
Highly Cited
2010
ABSTRACT Aspergillus fumigatus sterol 14-α demethylase (CYP51) isoenzymes A (AF51A) and B (AF51B) were expressed in Escherichia… Expand
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Highly Cited
2010
Highly Cited
2010
ABSTRACT Purified Candida albicans sterol 14-α demethylase (CaCYP51) bound the CYP51 substrates lanosterol and eburicol… Expand
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Highly Cited
2006
Highly Cited
2006
SUMMARY Sterol demethylation inhibitors (DMIs) represent one of the largest groups of systemic fungicides that have been used to… Expand
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Highly Cited
2004
Highly Cited
2004
OBJECTIVES The aim of this study was to identify changes in the gene expression profile of Candida albicans associated with the… Expand
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Highly Cited
2003
Highly Cited
2003
ABSTRACT The role of sterol mutations in the resistance of Candida albicans to antifungal agents has not been thoroughly… Expand
Highly Cited
1998
Highly Cited
1998
Metabolism of lanosterol (LAN), 24‐methylene‐24,25‐dihydrolanosterol (24‐methyleneDHL), dihydrolanosterol (DHL) and obtusifoliol… Expand
Highly Cited
1993
Highly Cited
1993
As in other pathogenic fungi, the major sterol synthesized by Cryptococcus neoformans var. neoformans is ergosterol. This yeast… Expand
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Highly Cited
1987
Highly Cited
1987
Candida albicans 6.4, which is resistant to both polyene and azole groups of antifungal antibiotics, has a larger lipid content… Expand