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Lanosterol

Known as: Lanosta-8,24-dien-3-ol, (3beta)-, Kryptosterol, Lanosterol [Chemical/Ingredient] 
A triterpene that derives from the chair-boat-chair-boat folding of 2,3-oxidosqualene. It is metabolized to CHOLESTEROL and CUCURBITACINS.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
The human lens is comprised largely of crystallin proteins assembled into a highly ordered, interactive macro-structure essential… Expand
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Highly Cited
2013
Highly Cited
2013
Significance We demonstrate that host-induced gene silencing (HIGS) targeting the fungal sterol 14α-demethylase (CYP51) genes… Expand
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Highly Cited
2009
Highly Cited
2009
The differences between the biosynthesis of sterols in higher plants and yeast/mammals are believed to originate at the… Expand
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Highly Cited
2005
Highly Cited
2005
Feedback control of cholesterol synthesis is mediated in part by sterol-induced binding of HMG CoA reductase to Insig proteins in… Expand
Highly Cited
2003
Highly Cited
2003
ABSTRACT Nuclear receptors are ligand-modulated transcription factors. On the basis of the completed human genome sequence, this… Expand
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Highly Cited
2000
Highly Cited
2000
The three-dimensional structure of lanosterol 14alpha-demethylase (P450(14DM), CYP51) of Candida albicans was modeled on the… Expand
Highly Cited
1998
Highly Cited
1998
ABSTRACT The cytochrome P-450 lanosterol 14α-demethylase (CYP51A1) of yeasts is involved in an important step in the biosynthesis… Expand
Highly Cited
1997
Highly Cited
1997
  • T. White
  • Antimicrobial agents and chemotherapy
  • 1997
  • Corpus ID: 2770989
Azole resistance in the pathogenic yeast Candida albicans is an emerging problem in the human immunodeficiency virus (HIV… Expand
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Highly Cited
1997
Highly Cited
1997
  • T. White
  • Antimicrobial agents and chemotherapy
  • 1997
  • Corpus ID: 14723954
Resistance to antifungal drugs, specifically azoles such as fluconazole, in the opportunistic yeast Candida albicans has become… Expand
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Highly Cited
1996
Highly Cited
1996
CHOLESTEROL and its oxysterol congeners are important constitu-ents of cell membranes and function as intermediates in several… Expand