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Lanosterol

Known as: Lanosta-8,24-dien-3-ol, (3beta)-, Kryptosterol, Lanosterol [Chemical/Ingredient] 
A triterpene that derives from the chair-boat-chair-boat folding of 2,3-oxidosqualene. It is metabolized to CHOLESTEROL and CUCURBITACINS.
National Institutes of Health

Related topics

Related topics

49 relations

Narrower (37)

23,24,25,26,27-pentanordihydrolanosterol24,25-oxidolanosterol25-aminolanosterol27-nor-24,25-dihydrolanosterol

Broader (2)

CholestadienesCholestanes
In BloodLanosterol:SCnc:Pt:Ser/Plas:QnProcess of secretionagonists

Papers overview

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2001
2001
Yeast Cytochrome P-450 Catalyzing Lanosterol 14 a-Demethylation
A form of cytochrome P-450 catalyzing lanosterol 14a-demethylation (tentatively called ‘P’45014DMn) was purified from microsomes… 
1986
1986
Oxidative demethylation of lanosterol in cholesterol biosynthesis: accumulation of sterol intermediates.
With [3H-24,25]-dihydrolanosterol as substrate, large-scale metabolic formation of intermediates of lanosterol demethylation was… 
1986
1986
A comparison of cycloartenol and lanosterol biosynthesis and metabolism by the Oomycetes
Representative members in each of the four orders of Oomycetes (Phytophthora cactorum, Peronosporales;Lagenidium callinectes, L… 
1984
1984
Cholesterol-induced growth stimulation, cell aggregation, and membrane properties of ascites tumor cells in culture.
Ascites tumor cells can be cultivated at a reduced serum concentration if cholesterol (2.50 mg per 100 ml of medium) is added to… 
1979
1979
Studies on the mechanism of lanosterol 14 alpha-demethylation. A requirement for two distinct types of mixed-function-oxidase systems.
Carbon monoxide inhibited the removal of C-32 of dihydrolanosterol (I), but not of its metabolites 5 alpha-lanost-8-ene-3 beta,32… 
1979
1979
Effects of a supernatant protein activator on microsomal squalene-2,3-oxide-lanosterol cyclase.
A soluble protein termed "supernatant protein factor" (SPF) that stimulates microsomal squalene epoxidase has been isolated in… 
1976
1976
Effect of a supernatant protein on microsomal squalene epoxidase and 2,3-oxidosqualene-lanosterol cyclase.
Squalene epoxidation catalyzed by rat liver microsomes requires oxygen NADPH, and the 105,000 x g supernatant (S105). The… 
1973
1973
The rôle of cytochrome P-450 in cholesterol biosynthesis.
The rates of cholesterol biosynthesis were studied in rat liver microsomal preparations incubated with [14C]lanosterol in the… 
1970
1970
Investigations on the biosynthesis of steroids and terpenoids. II. Role of 24-methylene derivatives in the biosynthesis of steroids and terpenoids.
24,25-Dihydro-24-methylenelanosterol has been synthesised from lanosterol and investigated as a potential precursor of eburicoic… 
1961
1961
Inhibition of cholesterol biogenesis by arsenite: preparation of labeled lanosterol
SUMMARY When mevalonic a~id-2-C'~ was incubated with rat liver homogenate with the usual cofactors plus 10-3 M arsenite, the…