Cholesterol-induced growth stimulation, cell aggregation, and membrane properties of ascites tumor cells in culture.

  title={Cholesterol-induced growth stimulation, cell aggregation, and membrane properties of ascites tumor cells in culture.},
  author={E. W. Haeffner and Christiane Hoffmann and M. Stoehr and H P Scherf},
  journal={Cancer research},
  volume={44 6},
Ascites tumor cells can be cultivated at a reduced serum concentration if cholesterol (2.50 mg per 100 ml of medium) is added to the culture medium. At serum concentrations of 3%, optimal growth properties are obtained; below 3%, cell cultures usually perish after a few days. Cells grown in the presence of added cholesterol have an elevated content of this molecule per cell as well as in the plasma membrane, and they also show a cholesterol concentration-dependent rate of proliferation… CONTINUE READING


Publications referenced by this paper.
Showing 1-10 of 39 references

The attraction of proteins for small moleculesand ions

G. Scalchard
Ann. NY JUNE 1984 2675 on April • 1984
View 4 Excerpts
Highly Influenced

Effect of low serum concentration with and without lipid supplementationon Karzel ascites tumor cell growth

C.J.K. Hoffmann, E. W. Haeffner
J. Cancer Res. Clin. Oncol., • 1981
View 1 Excerpt

Membranelipid fluidity as rate limiting mediated agglutinability of BALB/c 3T3 cells grown in media supplemented in the concanavalinA-medialedagglutinationof pyBHK cells

G. S. Rule, J. Kruuv, J. R. Lepock
Biochim.Biophys. wilh differenl phosphatidylcholines. Biochem. Biophys. Res. Commun., • 1980
View 1 Excerpt

Plasmamembrane heterogeneityin ascites tumor cells. Isolationof a light and a heavy membrane fraction of the glycogen-free Ehriich-Lettrésubstrain

E. W. Haeffner, K. Kolbe, D. Schroeter, N. Paweletz
Biochim. Biophys. Acta, • 1980
View 1 Excerpt

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