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drug response
Known as:
drug responses
, drugs response
, response to drug
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene…
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National Institutes of Health
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Related topics
Related topics
4 relations
Drug effect disorder
Drug resistance
drug susceptibility/resistance
Narrower (1)
drug transport
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
A Landscape of Pharmacogenomic Interactions in Cancer
F. Iorio
,
T. Knijnenburg
,
+36 authors
M. Garnett
Cell
2016
Corpus ID: 15520966
Highly Cited
2015
Highly Cited
2015
High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response
Hui Gao
,
Joshua M. Korn
,
+61 authors
W. Sellers
Nature Network Boston
2015
Corpus ID: 28275629
Profiling candidate therapeutics with limited cancer models during preclinical development hinders predictions of clinical…
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Highly Cited
2012
Highly Cited
2012
Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells
Wanjuan Yang
,
Jorge Soares
,
+14 authors
M. Garnett
Nucleic Acids Res.
2012
Corpus ID: 7953330
Alterations in cancer genomes strongly influence clinical responses to treatment and in many instances are potent biomarkers for…
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Highly Cited
2011
Highly Cited
2011
Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum
S. Bendall
,
Erin F. Simonds
,
+13 authors
G. Nolan
Science
2011
Corpus ID: 13833336
Simultaneous measurement of more than 30 properties in individual human cells is used to characterize signaling in the immune…
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Review
2008
Review
2008
Metabolomics: a global biochemical approach to drug response and disease.
R. Kaddurah-Daouk
,
B. Kristal
,
R. Weinshilboum
Annual Review of Pharmacology and Toxicology
2008
Corpus ID: 1989947
Metabolomics is the study of metabolism at the global level. This rapidly developing new discipline has important potential…
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Review
2007
Review
2007
The effect of cytochrome P450 metabolism on drug response, interactions, and adverse effects.
T. Lynch
,
Amy L. Price
American Family Physician
2007
Corpus ID: 33933519
Cytochrome P450 enzymes are essential for the metabolism of many medications. Although this class has more than 50 enzymes, six…
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Review
2005
Review
2005
Drug metabolism and variability among patients in drug response.
G. Wilkinson
New England Journal of Medicine
2005
Corpus ID: 21857991
Differences in drug responsiveness are common, often leading to challenges in optimizing the dosage regimen for a particular…
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Review
2004
Review
2004
Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response
J. Kirchheiner
,
K. Nickchen
,
+4 authors
J. Brockmöller
Molecular Psychiatry
2004
Corpus ID: 23403231
Genetic factors contribute to the phenotype of drug response. We systematically analyzed all available pharmacogenetic data from…
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Review
2003
Review
2003
Inheritance and drug response.
R. Weinshilboum
New England Journal of Medicine
2003
Corpus ID: 16665363
he promise of pharmacogenetics, the study of the role of in heritance in the individual variation in drug response, lies in its…
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Highly Cited
2003
Highly Cited
2003
Clopidogrel for Coronary Stenting Response Variability, Drug Resistance, and the Effect of Pretreatment Platelet Reactivity
P. Gurbel
,
K. Bliden
,
B. L. Hiatt
,
C. O'connor
Circulation
2003
Corpus ID: 1581105
Background Clopidogrel is administered to prevent stent thrombosis; however, the uniformity of platelet inhibition after…
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