drug transport

Known as: Drug Transport Process, drugs transport 
The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, into, out of or within a cell, or between… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Biological barriers to drug transport prevent successful accumulation of nanotherapeutics specifically at diseased sites… (More)
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Highly Cited
2010
Highly Cited
2010
Multidrug transporter proteins are best known for their contributions to chemoresistance through the efflux of anticancer drugs… (More)
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Review
2010
Review
2010
The permeability of biological membranes is one of the most important determinants of the pharmacokinetic processes of a drug… (More)
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Review
2009
Review
2009
In Gram-negative bacteria such as Escherichia coli and Pseudomonas aeruginosa, tripartite multidrug efflux systems extrude… (More)
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Highly Cited
2007
Highly Cited
2007
A major obstacle to successful chemotherapy is intrinsic or acquired multi-drug resistance (MDR). The most common cause of MDR… (More)
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Review
2001
Review
2001
The trend towards identification of poorly water-soluble and highly lipophilic candidate drug molecules has led to an increase in… (More)
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Highly Cited
2000
Highly Cited
2000
Molecular polar surface area (PSA), i.e., surface belonging to polar atoms, is a descriptor that was shown to correlate well with… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Although quinidine is known to elevate plasma digoxin concentrations, the mechanism underlying this interaction is not… (More)
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Review
1998
Review
1998
Lipid-soluble small molecules with a molecular mass under a 400-600-Da threshold are transported readily through the blood-brain… (More)
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Highly Cited
1990
Highly Cited
1990
Human colon adenocarcinoma (Caco-2) cells, when grown on semipermeable filters, spontaneously differentiate in culture to form… (More)
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