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dopamine biosynthetic process

Known as: dopamine biosynthesis, dopamine formation, dopamine synthesis 
The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of… (More)
National Institutes of Health

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Topic mentions per year

1976-2018
0102019762018

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Related mentions per year

Related mentions per year

1976-2018
197019801990200020102020
dopamine biosynthetic process
negative regulation of dopamine biosynthetic process
positive regulation of dopamine biosynthetic process
regulation of dopamine biosynthetic process

Papers overview

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Highly Cited
2013
Highly Cited
2013
Presynaptic striatal dopamine dysfunction in people at ultra-high risk for psychosis: findings in a second cohort.
BACKGROUND Using positron emission tomography (PET), we previously observed increases in 3,4-dihydroxy-6-[(18)F]fluoro-L… (More)
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Highly Cited
2012
Highly Cited
2012
Dopamine synthesis capacity in patients with treatment-resistant schizophrenia.
OBJECTIVE Elevated presynaptic striatal dopaminergic function is a robust feature of schizophrenia. However, the relationship… (More)
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Highly Cited
2011
Highly Cited
2011
Dopamine synthesis capacity before onset of psychosis: a prospective [18F]-DOPA PET imaging study.
OBJECTIVE While there is robust evidence of elevated dopamine synthesis capacity once a psychotic disorder has developed, little… (More)
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Highly Cited
2009
Highly Cited
2009
Striatal dopamine predicts outcome-specific reversal learning and its sensitivity to dopaminergic drug administration.
Individual variability in reward-based learning has been ascribed to quantitative variation in baseline levels of striatal… (More)
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Highly Cited
2005
Highly Cited
2005
Regulation of dopaminergic transmission and cocaine reward by the Clock gene.
Although there are clear interactions between circadian rhythms and drug addiction, mechanisms for such interactions remain… (More)
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Highly Cited
2002
Highly Cited
2002
A role for alpha-synuclein in the regulation of dopamine biosynthesis.
The alpha-synuclein gene is implicated in the pathogenesis of Parkinson's disease. Although alpha-synuclein function is uncertain… (More)
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Highly Cited
1998
Highly Cited
1998
Profound neuronal plasticity in response to inactivation of the dopamine transporter.
The dopamine transporter (DAT) plays an important role in calibrating the duration and intensity of dopamine neurotransmission in… (More)
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Highly Cited
1998
Highly Cited
1998
Inactivation of tyrosine hydroxylase by nitration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
The decrement in dopamine levels exceeds the loss of dopaminergic neurons in Parkinson's disease (PD) patients and experimental… (More)
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Highly Cited
1992
Highly Cited
1992
Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with Parkinson's disease.
BACKGROUND Parkinson's disease is characterized by the loss of midbrain dopamine neurons that innervate the caudate and the… (More)
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Highly Cited
1990
Highly Cited
1990
Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease.
Neural transplantation can restore striatal dopaminergic neurotransmission in animal models of Parkinson's disease. It has now… (More)
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