dodecenoyl-CoA delta-isomerase

Known as: Acetylene Allene Isomerase, Dodecenoyl Coenzyme A delta Isomerase, Dodecenoyl-Coenzyme A delta-Isomerase 
A carbon-carbon double bond isomerase that catalyzes the movement double bond from C3 to C2 of an unsaturated acyl-CoA. The enzyme plays a key role… (More)
National Institutes of Health

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ECI1 geneIn BloodProcess of secretionantagonists & inhibitors
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ECI2 protein, human

Papers overview

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2012
2012
Prolyl isomerase Pin1 promotes amyloid precursor protein (APP) turnover by inhibiting glycogen synthase kinase-3β (GSK3β) activity: novel mechanism for Pin1 to protect against Alzheimer disease.
Alzheimer disease (AD) is characterized by the presence of senile plaques of amyloid-β (Aβ) peptides derived from amyloid… (More)
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2012
2012
Prolyl isomerase Pin1 regulates neuronal differentiation via β-catenin.
The Wnt/β-catenin pathway promotes proliferation of neural progenitor cells (NPCs) at early stages and induces neuronal… (More)
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2011
2011
Systems virology identifies a mitochondrial fatty acid oxidation enzyme, dodecenoyl coenzyme A delta isomerase, required for hepatitis C virus replication and likely pathogenesis.
We previously employed systems biology approaches to identify the mitochondrial fatty acid oxidation enzyme dodecenoyl coenzyme A… (More)
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Highly Cited
2010
Highly Cited
2010
Differential impact of lipoxygenase 2 and jasmonates on natural and stress-induced senescence in Arabidopsis.
Jasmonic acid and related oxylipins are controversially discussed to be involved in regulating the initiation and progression of… (More)
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2009
2009
The Prolyl Isomerase Pin1 Regulates the NF-κB Signaling Pathway and Interleukin-8 Expression in Glioblastoma
The brain tumor glioblastoma (GBM) remains one of the most aggressive and devastating tumors despite decades of effort to find… (More)
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Review
2007
Review
2007
Prolyl isomerase, Pin1: new findings of post-translational modifications and physiological substrates in cancer, asthma and Alzheimer’s disease
The peptidyl prolyl cis/trans isomerase Pin1 specifically binds phosphorylated Ser/Thr-Pro protein motifs and catalyzes the cis… (More)
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2006
2006
Biosynthesis of C9-aldehydes in the moss Physcomitrella patens.
After wounding, the moss Physcomitrella patens emits fatty acid derived volatiles like octenal, octenols and (2E)-nonenal… (More)
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Highly Cited
2004
Highly Cited
2004
Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover.
Bim, a "BH3-only" protein, is expressed de novo following withdrawal of serum survival factors and promotes cell death. We have… (More)
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2002
2002
Carotenoid isomerase: a tale of light and isomers.
Carotenoids are terpenoid pigments containing systems of conjugated double bonds, each of which can exist in a cis or trans… (More)
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Highly Cited
1996
Highly Cited
1996
Structure of a dehydratase-isomerase from the bacterial pathway for biosynthesis of unsaturated fatty acids: two catalytic activities in one active site.
BACKGROUND Escherichia coli beta-hydroxydecanoyl thiol ester dehydrase (dehydrase) is essential to the biosynthesis of… (More)
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