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dl1520

National Institutes of Health

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ONYX015

Papers overview

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2012
2012
[Antitumour efficacy of a novel oncolytic adenovirus Ad-TD-RFP for human nasopharyngeal carcinoma].
OBJECTIVE To evaluate the antitumor efficacy of Ad-TD-RFP for human nasopharyngeal carcinoma cells (C666-1) in vitro and in vivo… 
2008
2008
Analysis of oncolytic adenovirus dl922-947 effects on anaplastic thyroid carcinoma cells (ATC) and potentialtherapeutic associations
2005
2005
Clinical trials: The sensitizing side of Onyx-015
New clinical trial data on the use of the ONYX-015 adenovirus as a chemosensitizing agent indicate that further study of this… 
2005
2005
Cell Killing and Growth Inhibition of Oncolytic Virus dl1520 on Hepatic Carcinoma Cells Hep3B In vitro
Objective To evaluate the efficiency of cell killing and growth inhibition of oncolytic virus dl1520 on hepatic carcinoma cells… 
2003
2003
Replication of an E 1 B 55-Kilodalton Protein-Deficient Adenovirus ( ONYX-015 ) Is Restored by Gain-of-Function Rather than Loss-of-Function p 53 Mutants
ONYX-015 (dl1520) is an E1B 55-kilodalton protein-deficient replicating adenovirus that is currently in clinical trials as an… 
2001
2001
The cytotoxic effect of E1B 55-kDa mutant adenovirus on human hepatocellular carcinoma cell lines
It has been suggested the E1B 55 kDa mutant adenovirus dl1520 can selectively killp53-deficient human tumor cells. In this study… 
1999
1999
Selective and Nonselective Replication of an E 1 B-deleted Adenovirus in Hepatocellular Carcinoma 1
An E1B gene-attenuated adenovirus ( dl1520) has been proposed to have a selective cytolytic activity in cancer cells with a…