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diphthamide

Known as: 1H-Imidazole-2-propanaminium, alpha-(aminocarbonyl)-4-(2-amino-2-carboxyethyl)-N,N,N-trimethyl-, hydroxide, inner salt, 2-(3-carboxyamido-3-(trimethylammonio)propyl)histidine 
National Institutes of Health

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2 relations

Broader (1)

Histidine
analogs & derivatives

Papers overview

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Highly Cited
2006
Highly Cited
2006
Dph3, a Small Protein Required for Diphthamide Biosynthesis, Is Essential in Mouse Development
ABSTRACT The translation elongation factor 2 in eukaryotes (eEF-2) contains a unique posttranslationally modified histidine… 
Review
2005
Review
2005
OVCA1: tumor suppressor gene.
1996
1996
A cDNA from the ovarian cancer critical region of deletion on chromosome 17p13.3.
Highly Cited
1992
Highly Cited
1992
Saccharomyces cerevisiae elongation factor 2. Genetic cloning, characterization of expression, and G-domain modeling.
1988
1988
Expression of diphtheria toxin fragment A and hormone-toxin fusion proteins in toxin-resistant yeast mutants.
Mutants of the eukaryote Saccharomyces cerevisiae, previously selected for resistance to diphtheria toxin, were investigated for… 
1987
1987
Highly frequent single amino acid substitution in mammalian elongation factor 2 (EF-2) results in expression of resistance to EF-2-ADP-ribosylating toxins.
Highly Cited
1984
Highly Cited
1984
In vitro biosynthesis of diphthamide, studied with mutant Chinese hamster ovary cells resistant to diphtheria toxin
Diphthamide, a unique amino acid, is a post-translational derivative of histidine that exists in protein synthesis elongation… 
1984
1984
ADP‐ribosyltransferase from beef liver which ADP‐ribosylates elongation factor‐2
Highly Cited
1983
Highly Cited
1983
Occurrence of diphthamide in archaebacteria
We examined the nature of the diphtheria toxin fragment A recognition site in the protein synthesis translocating factor present… 
Highly Cited
1980
Highly Cited
1980
ADP-ribosylation of elongation factor 2 by diphtheria toxin. NMR spectra and proposed structures of ribosyl-diphthamide and its hydrolysis products.
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