diphthamide

Known as: 1H-Imidazole-2-propanaminium, alpha-(aminocarbonyl)-4-(2-amino-2-carboxyethyl)-N,N,N-trimethyl-, hydroxide, inner salt, 2-(3-carboxyamido-3-(trimethylammonio)propyl)histidine 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2018
0519802018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Loss-of-function genetic screens in model organisms have elucidated numerous biological processes, but the diploid genome of… (More)
Is this relevant?
2008
2008
The intracellular target of diphtheria toxin is a modified histidine residue, diphthamide, in the translation elongation factor… (More)
  • figure 1
  • figure 3
  • figure 2
  • table 1
  • figure 4
Is this relevant?
2008
2008
Diphthamide is a post-translational derivative of histidine in protein synthesis elongation factor-2 (eEF-2) that is present in… (More)
Is this relevant?
2004
2004
Diphthamide, a posttranslational modification of translation elongation factor 2 that is conserved in all eukaryotes and… (More)
  • figure 1
  • table 1
  • table 2
  • table 4
  • figure 3
Is this relevant?
1993
1993
A gene involved in diphthamide biosynthesis, DPH2, was cloned from Saccharomyces cerevisiae by complementation of a diphthamide… (More)
Is this relevant?
1992
1992
A mutant of Saccharomyces cerevisiae defective in the S-adenosylmethionine (AdoMet)-dependent methyltransferase step of… (More)
Is this relevant?
1984
1984
Diphthamide, a unique amino acid, is a post-translational derivative of histidine that exists in protein synthesis elongation… (More)
Is this relevant?
1983
1983
Diphthamide, the post-translational amino acid derivative in the diphtheria toxin-modification site of protein synthesis… (More)
Is this relevant?
1981
1981
Diphtheria toxin inactivates protein synthesis elongation factor 2 by catalyzing the ADP-ribosylation of a novel derivative of… (More)
Is this relevant?
1980
1980
NMR spectral analysis of the novel amino acid, diphthamide, in elongation factor 2 which is ADP-ribosylated by diphtheria toxin… (More)
Is this relevant?