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diisopropyl 1,3-dithiol-2-ylidenemalonate

Known as: 1,3-dithiol-2-ylidenepropanedioic acid, bis(1-methylethyl) ester, malotilate 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

MalonatesSulfhydryl Compounds

Narrower (1)

NKK 105

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2001
2001
CYP11B2 Expression in Rat Liver and the Effect of Spironolactone on Hepatic Fibrogenesis
Objective: In consideration of the hypothetical possibility that locally produced aldosterone is likely to take an active part in… 
1996
1996
The effect of malotilate on type III and type IV collagen, laminin and fibronectin metabolism in dimethylnitrosamine-induced liver fibrosis in the rat.
Review
1994
Review
1994
Inhibition of hepatic fibrogenesis: a review of pharmacologic candidates.
Therapeutic attempts with anti-fibrotic drugs are still at an experimental stage. The clinical efficacies of most agents listed… 
Review
1990
Review
1990
Therapy for Hepatic Fibrosis
Although there is no established therapy for the fibrogenesis of hepatic cirrhosis, many potential therapies are now emerging… 
1988
1988
Use of hepatocyte co-cultures in the assessment of drug toxicity from chronic exposure.
1. In rat hepatocyte cultures, clonidine and malotilate were cytotoxic at 170 microM but did not induce changes at lower… 
1987
1987
Preventive effect of malotilate on carbon tetrachloride-induced liver damage and collagen accumulation in the rat.
Malotilate is a new drug suggested for use in chronic liver diseases. It is shown here to prevent liver damage caused by CCl4… 
1982
1982
Effect of malotilate (diisopropyl 1,3-dithiol-2-ylidenemalonate) on the protein synthesis in rat liver.
The effect of malotilate (diisopropyl 1,3-dithiol-2-ylidenemalonate) on the protein synthesis in rat liver was studied in vivo… 
1982
1982
Stimulatory effect of cytochrome b5 induced by p-nitroanisole and diisopropyl 1,3-dithiol-2-ylidenemalonate on rat liver microsomal drug hydroxylations.
The relationship between the changes in the amount of the components of the liver microsomal electron transport systems and drug… 
1981
1981
Effect of diisopropyl 1,3-dithiol-2-ylidenemalonate (NKK-105) on fatty liver induced by carbon tetrachloride.
The therapeutic effect of diisopropyl 1,3-dithiol-2-ylidenemalonate (NKK-105) on the fatty liver induced by carbon tetrachloride… 
1980
1980
Effect of diisopropyl 1,3-dithiol-2-ylidenemalonate on microsomal electron transport system in rat liver.
Effect of diisopropyl 1,3-dithiol-2-ylidenemalonate (NKK-105) on the components of rat liver microsomal electron transport system… 
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