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dihydrosafrole

Known as: 1,3-benzodioxole, 5-propyl- 
 
National Institutes of Health

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Broader (1)

Safrole
analogs & derivatives

Papers overview

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2010
2010
Larvicidal and structure-activity studies of natural phenylpropanoids and their semisynthetic derivatives against the tobacco armyworm Spodoptera litura (Fab.) (Lepidoptera: Noctuidae).
The larvicidal activity of 18 phenylpropanoids, 1-18, including phenylpropenoate, phenylpropenal, phenylpropene, and their… Expand
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1996
1996
The prevention of CCl4-induced liver necrosis in mice by naturally occurring methylenedioxybenzenes.
Methylenedioxybenzenes (MDBs) and structurally related alkenylbenzenes were compared for their effectiveness in preventing carbon… Expand
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1987
1987
Inhibition of cytochrome P-450c-mediated benzo[a]pyrene hydroxylase and ethoxyresorufin O-deethylase by dihydrosafrole.
1. Inhibitory activity of dihydrosafrole towards benzo[a]pyrene (BP) hydroxylase activity in hepatic microsomes from beta… Expand
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1987
1987
In vivo metabolism of nasally instilled dihydrosafrole [1-(3,4-methylenedioxyphenyl)propane] in dogs and monkeys.
Nasal metabolism of inhaled material may influence its biological fate and toxicity. The purpose of this study was to investigate… Expand
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1985
1985
Spectral and inhibitory interactions of methylenedioxyphenyl and related compounds with purified isozymes of cytochrome P-450.
Spectral and inhibitory interactions of two methylenedioxyphenyl (MDP) compounds (dihydrosafrole (DHS) and 4,5-dichloro-1,2… Expand
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1983
1983
Effects of dihydrosafrole on cytochromes P-450 and drug oxidation in hepatic microsomes from control and induced rats.
Changes in cytochromes P-450, aminopyrine N-demethylase (APDM), aromatic hydrocarbon (benzo[a]pyrene) hydroxylase (AHH), and type… Expand
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1982
1982
Metabolism of isosafrole and dihydrosafrole in the rat.
The urinary metabolites of isosafrole (1,2-methylenedioxy-4-propenylbenzene) and dihydrosafrole (1,2-methylenedioxy-4… Expand
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1970
1970
Importance of demethylenation in the metabolism in vivo and in vitro of methylenedioxyphenyl synergists and related compounds in mammals.
Abstract The major metabolic pathway for piperonyl butoxide, the sulfoxide diastereo-isomers, dihydrosafrole, safrole and… Expand
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1965
1965
TOXIC PROPERTIES OF COMPOUNDS RELATED TO SAFROLE.
Abstract Dihydrosafrole on chronic feeding produced benign and malignant esophageal tumors. Safrole is a hepatic carcinogen… Expand
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1964
1964
A COMPARISON OF THE TOXICITY OF SOME ALLYL, PROPENYL, AND PROPYL COMPOUNDS IN THE RAT.
Summary The toxicity in the rat of a number of allyl, propenyl, propyl, and related compounds has been compared using as criteria… Expand
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