Skip to search formSkip to main contentSkip to account menu

difloxacin

Known as: 1-FFMPOC, 6-fluoro-1-(4-fluorophenyl)-7-(4-methyl-1-piperazinyl)-1,4-dihydro-4-quinolone-3-carboxylic acid, 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid 
National Institutes of Health

Related topics

Related topics

7 relations

Narrower (2)

A 56619Dicural

Broader (1)

Ciprofloxacin
Difloxacin:Susc:Pt:Isolate:OrdQnDifloxacin:Susc:Pt:Isolate:OrdQn:MICanalogs & derivativesdifloxacin hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Pharmacokinetics and milk penetration of difloxacin after intravenous, subcutaneous and intramuscular administration to lactating goats.
The single-dose disposition kinetics of difloxacin were determined in clinically normal lactating goats (n = 6) after intravenous… 
Highly Cited
2006
Highly Cited
2006
Confirmatory and quantitative analysis using experimental design for the extraction and liquid chromatography-UV, liquid chromatography-mass spectrometry and liquid chromatography-mass spectrometry…
2005
2005
Efficacy of difloxacin against respiratory infections of lambs.
The trial was carried out in a sheep flock with mixed Mannheimia haemolytica/Mycoplasma spp. respiratory infection; 60 lambs were… 
Highly Cited
2002
Highly Cited
2002
Multiresidue analysis of fluoroquinolone antibiotics in chicken tissue using liquid chromatography-fluorescence-multiple mass spectrometry.
Highly Cited
1992
Highly Cited
1992
Morphologic and Biochemical Changes in Articular Cartilages of Immature Beagle Dogs Dosed with Difloxacin
Quinolones are efficacious antibacterial compounds, but they have been associated with arthralgia in human patients… 
Highly Cited
1989
Highly Cited
1989
Comparative antimycobacterial activities of difloxacin, temafloxacin, enoxacin, pefloxacin, reference fluoroquinolones, and a new macrolide, clarithromycin
The activities of fluoroquinolones and a new macrolide against 30 clinical isolates of Mycobacterium tuberculosis were determined… 
1988
1988
Multicenter in vitro evaluation of lomefloxacin (NY-198, SC-47111), including tests against nearly 7,000 bacterial isolates and preliminary recommendations for susceptibility testing.
Highly Cited
1986
Highly Cited
1986
Difloxacin metabolism and pharmacokinetics in humans after single oral doses
By using high-performance liquid chromatography, the metabolism and pharmacokinetics of difloxacin were characterized in humans… 
Highly Cited
1986
Highly Cited
1986
In vitro evaluation of A-56619 (difloxacin) and A-56620: new aryl-fluoroquinolones
The in vitro antibacterial potencies of A-56619 and A-56620, two new aryl-fluoroquinolones, were compared with the potency of… 
1986
1986
Factors influencing the in vitro activity of two new aryl-fluoroquinolone antimicrobial agents, difloxacin (A-56619) and A-56620
The in vitro activity of difloxacin (A-56619) and A-56620, two new aryl-difluoroquinolones, was decreased by magnesium at 9 mM… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)