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diethylmethylnitrosourea

Known as: DEMNU, N,N-diethyl-N'-methyl-N'-nitrosourea, nitrosomethyldiethylurea 
National Institutes of Health

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Nitrosourea Compounds

Papers overview

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1990
1990
[The pre- and postnatal carcinogenic effect of 3,3-diethyl-1-methyl-1-nitrosourea (DEMNU) in rats following intravenous application].
The pre- and postnatal administration of DEMNU induces a high frequency of tumors when applied via the intravenous route, and the… 
1989
1989
Serine hydrolases activate/inactivate trisubstituted nitrosoureas in dependence on intra- and extracellular enzyme location: an SCE study in Chinese hamster V79-E cells.
Trisubstituted nitrosoureas are very stable in aqueous systems. But they are potent genotoxins in Chinese hamster V79-E cells, if… 
1985
1985
Carcinogenic effect of nitrosoalkylureas and nitrosoalkylcarbamates in Syrian hamsters.
Three nitrosoalkylureas, two nitrosotrialkylureas, and three nitrosoalkylcarbamates were given to Syrian golden hamsters by… 
1984
1984
The carcinogenic effect of 1,1-diethyl-3-methyl-3-nitrosourea in Syrian golden hamsters.
1984
1984
Studies by means of the SCE assay in V79-E Chinese hamster cells on the mode of action of tri-substituted nitrosoureas.
1981
1981
The carcinogenic effect of 1,1-diethyl-3-methyl-3-nitrosourea in European hamsters.
1980
1980
Carcinogenicity of nitrosotrialkylureas in Fischer 344 rats.
Three nitrosotrialkylureas were administered to female F344 rats as approximately 1-mM solutions in drinking water… 
1975
1975
Induction of neurogenic tumors by nitrosotrialkylureas in rats
Four nitrosotrialkylureas were each fed to groups of 15 male and 15 female Sprague-Dawley rats for 50 weeks in drinking water at… 
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