didemnins

 

Topic mentions per year

Topic mentions per year

1983-2017
02419832017

Papers overview

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2012
2012
The anti-neoplastic agent didemnin B from the Caribbean tunicate Trididemnum solidum was the first marine drug to be clinically… (More)
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Review
2012
Review
2012
Since the discovery and isolation of the didemnin family of marine depsipeptides in 1981, the synthesis and biological activity… (More)
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2004
2004
Didemnins and tamandarins are closely related marine natural products with potent inhibitory effects on protein synthesis and… (More)
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2004
2004
A new class of marine compounds, the didemnins, with potent antitumor activity has been identified. They share the novel… (More)
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2001
2001
The synthesis and antitumor activity of a novel didemnin B analogue containing a psi[CH2NH] amide bond surrogate between N-Me-D… (More)
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2001
2001
The synthesis of four benzophenone-containing analogues of the antiproliferative natural product didemnin B is presented. In… (More)
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2000
2000
Synthetic and naturally occurring didemnins are potent and specific inhibitors of protein synthesis in vitro. Structure-activity… (More)
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1996
1996
Bioactivities of 42 didemnin congeners, either isolated from the marine tunicates Trididemnun solidum and Aplidium albicans or… (More)
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1995
1995
An X-ray crystal analysis of phi-lactone N-¿1-¿N-¿4-¿[3- hydroxy-5-methyl-1-oxo-4-(N-L-threonylamino)heptyl]- oxy¿-2,5-dimethyl-1… (More)
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Review
1988
Review
1988
Didemnins A, B, and C, cyclic depsipeptides previously reported by our laboratory from the Caribbean tunicate Trididemnum solidum… (More)
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