Skip to search formSkip to main contentSkip to account menu

dictyostatin

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Neurodegenerative disorders referred to as tauopathies, which includes Alzheimer’s disease (AD), are characterized by insoluble… 
2013
2013
Inclusions comprising the microtubule (MT)-stabilizing protein, tau, are found within neurons in the brains of patients with… 
2013
2013
In 1994 Petit reported the isolation and anti-cancer activity of the marine sponge-derived macrolide dictyostatin.[1] Wright… 
Highly Cited
2010
Highly Cited
2010
The dictyostatins are a promising class of potential anti-cancer drugs because they are powerful microtubule-stabilizing agents… 
Highly Cited
2008
Highly Cited
2008
A protocol based on a combination of NMR experimental data with molecular mechanics calculations and docking procedures has been… 
2007
2007
Abstract Eleutherobin and dictyostatin are antimitotic compounds which exert their cytotoxic activity by a taxol-like mode of… 
2007
2007
The structure-activity relationship of the crucial C16 region of (-)-dictyostatin was established through total synthesis of… 
Highly Cited
2006
Highly Cited
2006
A convergent total synthesis of dictyostatin is described. Key features of the synthesis include the use of titanium-mediated… 
Highly Cited
2005
Highly Cited
2005
(-)-Dictyostatin is a sponge-derived, 22-member macrolactone natural product shown to cause cells to accumulate in the G2/M phase… 
Highly Cited
2002
Highly Cited
2002
[structure: see text] Two hybrid analogues of discodermolide and dictyostatin (3, 26) have been designed and synthesized. These…