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desisobutyrylciclesonide

Known as: des-CIC, des-ciclesonide, desisobutyryl-ciclesonide 
 
National Institutes of Health

Papers overview

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2009
2009
Allometric modeling of ciclesonide, a nonhalogenated glucocorticoid, and its active metabolite, desisobutyrylciclesonide, using animal-derived pharmacokinetic parameters.
Ciclesonide, a novel glucocorticosteroid, through a rapid metabolism to desisobutyryl-ciclesonide (des-ciclesonide), provides an… Expand
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2008
2008
Transrepression and transactivation potencies of inhaled glucocorticoids.
The anti-inflammatory activity of inhaled glucocorticoids is primarily mediated through transrepression of pro-inflammatory… Expand
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Review
2006
Review
2006
Pharmacologic characteristics and adrenal suppression with newer inhaled corticosteroids: A comparison of ciclesonide and fluticasone propionate.
BACKGROUND Inhaled corticosteroids (ICSs) are the most potent anti-inflammatory choice for patients with asthma. Selecting the… Expand
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2005
2005
Lack of pharmacokinetic drug-drug interaction between ciclesonide and erythromycin.
OBJECTIVE To investigate whether systemic exposure to desisobutyrylciclesonide (des-CIC) (the pharmacologically active metabolite… Expand
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