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deoxyribonucleotide metabolic process

Known as: deoxyribonucleotide metabolism 
The chemical reactions and pathways involving a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose… Expand
National Institutes of Health

Papers overview

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Review
2015
Review
2015
Deoxyribonucleotide metabolism, mutagenesis and cancer
Cancer was recognized as a genetic disease at least four decades ago, with the realization that the spontaneous mutation rate… Expand
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2011
2011
Quantitative analysis of thymidine kinase 1 and 5'(3')-deoxyribonucleotidase mRNA expression: the role of fluorothymidine uptake.
BACKGROUND Thymidine kinase 1 (TK1) and 5'(3')-deoxyribonucleotidase (dNT1) regulate the metabolism of thymidine and its analogs… Expand
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2009
2009
Reversible tetramerization of human TK1 to the high catalytic efficient form is induced by pyrophosphate, in addition to tripolyphosphates, or high enzyme concentration.
Thymidine kinase (TK1) is a key enzyme in the salvage pathway of deoxyribonucleotide metabolism, catalyzing the first step in the… Expand
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Highly Cited
1995
Highly Cited
1995
Mimosine Arrests DNA Synthesis at Replication Forks by Inhibiting Deoxyribonucleotide Metabolism (*)
Mimosine has been reported to specifically prevent initiation of DNA replication in the chromosomes of mammalian nuclei. To test… Expand
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1989
1989
Organization of T4 bacteriophage genes and gene products involved in DNA precursor biosynthesis
Approved: Redacted for Privacy Bacteriophage T4 gene 42 encodes dCMP hydroxymethylase, an enzyme unique to the… Expand
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1986
1986
Modification of ribonucleotide and deoxyribonucleotide metabolism in interferon-treated human B-lymphoblastoid cells.
The effect of recombinant interferon-alpha 2 (IFN-alpha 2) (50 U/ml) on the cell cycle, nucleotide metabolism, and protein and… Expand
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1985
1985
Pyrimidine deoxyribonucleotide metabolism in Acholeplasma laidlawii B-PG9.
Extracts of Acholeplasma laidlawii B-PG9 were examined for the enzymes associated with the interconversion of the pyrimidine… Expand
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1985
1985
Adenine ribo- and deoxyribonucleotide metabolism in human erythrocytes, B- and T-lymphocyte cell lines, and monocyte-macrophages.
Ordinarily packaged in DNA, adenine deoxyribonucleotides are preferentially concentrated in erythrocyte and lymphocyte cytosol in… Expand
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1983
1983
Purine and pyrimidine metabolism in human T lymphocytes. Regulation of deoxyribonucleotide metabolism.
Purine and pyrimidine deoxyribonucleoside metabolism was studied in G1 and S phase human thymocytes and compared with that of the… Expand
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1980
1980
Alterations in deoxyribonucleotide metabolism in cultured cells with ribonucleotide reductase activities refractory to feedback inhibition by 2'-deoxyadenosine triphosphate.
 
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