J. Barankiewicz

Publications65
h-index18
Citations1,039
Highly Influential Citations25
Claim Author Page
Author pages are created from data sourced from our academic publisher partnerships and public sources.

Recommended Authors

  • A. Cohen
  • 154 Publications, 6,683 Citations
  • J. Henderson
  • 267 Publications, 5,523 Citations
  • A. R. Paterson
  • 156 Publications, 5,070 Citations
  • E. Gelfand
  • 1,039 Publications, 38,750 Citations
  • Publications
  • Influence
Adenosine kinase inhibitors as a novel approach to anticonvulsant therapy.
Adenosine levels increase at seizure foci as part of a postulated endogenous negative feedback mechanism that controls seizure activity through activation of A1 adenosine receptors. Agents that… Expand
  • 88
  • 10
  • PDF
Extracellular nucleotide catabolism in human B and T lymphocytes. The source of adenosine production.
Extracellular nucleotide degradation was studied in intact human B and T lymphocyte subpopulations and in lymphoblastoid cell lines. Cells of B lymphocyte lineage showed high nucleotide degrading… Expand
  • 84
  • 2
Inhibition of neutrophil adhesion by adenosine and an adenosine kinase inhibitor. The role of selectins.
Adenosine and adenosine analogues exhibit anti-inflammatory effects in vitro and in vivo, but their usefulness is limited by profound cardiovascular side effects. Therefore, we synthesized inhibitors… Expand
  • 113
  • 2
Regulation of adenosine concentration and cytoprotective effects of novel reversible adenosine deaminase inhibitors.
The physiological role of adenosine (Ado) is well known. Although a number of pharmacological attempts have been made to manipulate Ado concentrations in ischemic conditions in different tissues,… Expand
  • 39
  • 2
Purine and pyrimidine metabolism in human T lymphocytes. Regulation of deoxyribonucleotide metabolism.
Purine and pyrimidine deoxyribonucleoside metabolism was studied in G1 and S phase human thymocytes and compared with that of the more mature T lymphocytes from peripheral blood. Both thymocyte… Expand
  • 126
  • 1
Evidence for active purine nucleoside cycles in human mononuclear cells and cultured fibroblasts.
Several aspects of purine metabolism were studied in peripheral blood mononuclear cells and fibroblasts from a patient with purine nucleoside phosphorylase deficiency and compared to cells from… Expand
  • 19
  • 1
Establishment and characterization of adenosine deaminase-deficient human T cell lines.
We have established long term cell lines from a patient with adenosine deaminase (ADA)-deficient severe combined immunodeficiency by stimulation of blood and bone marrow cells with PHA and IL-2… Expand
  • 36
  • 1
Purine nucleotide metabolism in phytohemagglutinin-induced human T lymphocytes.
The comprehensive studies of purine nucleotide metabolism were done in nonstimulated and phytohemagglutinin (PHA)-stimulated human peripheral blood T lymphocytes. Nonstimulated lymphocytes synthesize… Expand
  • 30
  • 1
Metabolic consequences of DNA damage: alteration in purine metabolism following poly(ADP ribosyl)ation in human T-lymphoblasts.
The effect of DNA damage caused by N-methyl-N'-nitro-nitrosoguanidine (MNNG) on poly(ADP-ribose) synthesis, NAD levels, and purine nucleotide metabolism was studied in human T-lymphoblasts. Excessive… Expand
  • 16
  • 1
Purine salvage in cotyledons of germinating lupin seeds
Purine metabolism is much less elucidated in plants [ 1,2] than in animal tissues. In contrast to animal tissues, in plants adenosine is hydrolyzed to adenine and ribose by adenosine nucleosidase (EC… Expand
  • 36
  • 1