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deoxyhypusine synthase activity

Known as: eIF-5A-deoxyhypusine synthase activity, [eIF-5A]-deoxyhypusine synthase activity, spermidine:eIF5A-lysine 4-aminobutyltransferase (propane-1,3-diamine-forming) activity 
Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. Four sub-reactions have… Expand
National Institutes of Health

Papers overview

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2014
2014
We report the discovery of a fluorogenic dye, N1,N3-di(2-aminidonaphthalen-6-yl) propane-1,3-diamine, MitoBlue, which selectively… Expand
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2011
2011
Deoxyhypusine synthase catalyzes an unusual protein modification reaction. A portion of spermidine is covalently added to one… Expand
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2006
2006
Although much has been unravelled with regards to the mechanisms of proteolysis of exogenously derived antigen for presentation… Expand
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Highly Cited
2005
Highly Cited
2005
Development of drug resistance from mutations in the targeted viral proteins leads to continuation of viral production by… Expand
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2004
2004
Formation constants of copper(II), zinc(II), calcium(II) and gadolinium(III) with N,N'-bis(2-hydroxyiminopropionyl) propane-1,3… Expand
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1997
1997
Hypusine formation on the eukaryotic initiation factor 5A (eIF-5A) precursor is ubiquitously present in eukaryotic cells and… Expand
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