deoxyhypusine synthase

Known as: DHS, DHPS, EC 2.5.1.46 
Deoxyhypusine synthase (369 aa, ~41 kDa) is encoded by the human DHPS gene. This protein plays a role in the synthesis of deoxyhypusine and the post… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1954-2017
051019542016

Papers overview

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2013
2013
Polyamine biosynthesis is a key drug target in African trypanosomes. The "resurrection drug" eflornithine… (More)
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2008
Highly Cited
2008
The generality and spectrum of chromatin-remodeling requirements for nuclear receptor function are unknown. We have characterized… (More)
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2003
2003
Deoxyhypusine synthase catalyzes the first step in hypusine (N epsilon-(4-amino-2-hydroxybutyl)lysine) synthesis in a single… (More)
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2003
2003
Sphingolipid metabolism is implicated to play an important role in apoptosis. Here we show that dihydrosphingosine (DHS) and… (More)
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2002
Highly Cited
2002
The nectrotrophic fungus Alternaria alternata f.sp. lycopersici infects tomato plants of the genotype asc/asc by utilizing a host… (More)
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1995
1995
Deoxyhypusine synthase is the first enzyme involved in the post-translational formation of hypusine, a unique amino acid that… (More)
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1995
1995
Deoxyhypusine synthase catalyzes the formation of deoxyhypusine residue on the eIF-5A precursor using spermidine as the substrate… (More)
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1994
Highly Cited
1994
The enzyme dihydropteroate synthetase (DHPS) from Plasmodium falciparum is involved in the mechanism of action of the sulfone… (More)
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1992
1992
The Escherichia coli gene coding for dihydropteroate synthase (DHPS) has been cloned and sequenced. The protein has 282 amino… (More)
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1989
1989
A combination of surface monolayer, scanning calorimetry, 31P NMR, and spin-label ESR techniques has been used to monitor the… (More)
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