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deoxyhypusine synthase
Known as:
DHS
, DHPS
, EC 2.5.1.46
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Deoxyhypusine synthase (369 aa, ~41 kDa) is encoded by the human DHPS gene. This protein plays a role in the synthesis of deoxyhypusine and the post…
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National Institutes of Health
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Related topics
Related topics
10 relations
Amino Acid Biosynthesis
DHPS gene
DPYS gene
Enzyme Gene
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Broader (1)
Oxidoreductases Acting on CH-NH Group Donors
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
DHS (Trans-4,4’-Dihydroxystilbene) Suppresses DNA Replication and Tumor Growth by Inhibiting RRM2 (Ribonucleotide Reductase Regulatory Subunit M2)
Chi-Wei Chen
,
Yongming Li
,
+10 authors
Wenge Zhu
Oncogene
2018
Corpus ID: 54459569
DNA replication machinery is responsible for accurate and efficient duplication of the chromosome. Since inhibition of DNA…
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Highly Cited
2017
Highly Cited
2017
Late-Stage C-H Alkylation of Heterocycles and 1,4-Quinones via Oxidative Homolysis of 1,4-Dihydropyridines.
Álvaro Gutiérrez-Bonet
,
C. Remeur
,
J. K. Matsui
,
G. Molander
Journal of the American Chemical Society
2017
Corpus ID: 207181324
Under oxidative conditions, 1,4-dihydropyridines (DHPs) undergo a homolytic cleavage, forming exclusively a Csp3-centered radical…
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2015
2015
The novel synthesis of magnetically chitosan/carbon nanotube composites and their catalytic applications.
Z. Zarnegar
,
J. Safari
International journal of biological…
2015
Corpus ID: 40440148
2015
2015
Structural characterization of new Schiff bases of sulfamethoxazole and sulfathiazole, their antibacterial activity and docking computation with DHPS protein structure.
S. Mondal
,
S. Mandal
,
T. Mondal
,
C. Sinha
Spectrochimica acta. Part A, Molecular and…
2015
Corpus ID: 22679593
Review
2011
Review
2011
Deoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling
Andrew T. Templin
,
B. Maier
,
Y. Nishiki
,
S. Tersey
,
R. Mirmira
Cell cycle
2011
Corpus ID: 22860892
Deoxyhypusine synthase (DHS) catalyzes the post-translational formation of the amino acid hypusine. Hypusine is unique to the…
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2009
2009
Identification and Characterization of a Novel Deoxyhypusine Synthase in Leishmania donovani*
B. Chawla
,
A. Jhingran
,
+5 authors
R. Madhubala
The Journal of Biological Chemistry
2009
Corpus ID: 23913961
Deoxyhypusine synthase, an NAD+-dependent enzyme, catalyzes the first step in the post-translational synthesis of an unusual…
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Highly Cited
2004
Highly Cited
2004
Constitutive and seed-specific expression of a maize lysine-feedback-insensitive dihydrodipicolinate synthase gene leads to increased free lysine levels in rice seeds
Soo In Lee
,
H. U. Kim
,
+4 authors
Hoil Kim
Molecular Breeding
2004
Corpus ID: 22875622
In order to improve the nutritional value of rice, we prepared transgenic rice plants with a lysine-feedback-insensitive maize…
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Highly Cited
2002
Highly Cited
2002
Folate synthesis in higher-plant mitochondria: coupling between the dihydropterin pyrophosphokinase and the dihydropteroate synthase activities.
J. Mouillon
,
S. Ravanel
,
R. Douce
,
F. Rébeillé
The Biochemical journal
2002
Corpus ID: 11435447
The plant enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase/7,8-dihydropteroate synthase (HPPK/DHPS) is a mitochondrial…
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Highly Cited
1995
Highly Cited
1995
Deoxyhypusine Synthase from Rat Testis: Purification and Characterization (*)
E. Wolff
,
Y. B. Lee
,
S. I. Chung
,
J. E. Folk
,
M. H. Park
The Journal of Biological Chemistry
1995
Corpus ID: 23068025
Deoxyhypusine synthase is the first enzyme involved in the post-translational formation of hypusine, a unique amino acid that…
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Highly Cited
1995
Highly Cited
1995
Calcium Binding in the Pore of L-type Calcium Channels Modulates High Affinity Dihydropyridine Binding (*)
B. Z. Peterson
,
W. Catterall
The Journal of Biological Chemistry
1995
Corpus ID: 11601227
The pore-forming α1 subunit of L-type voltage-gated Ca channels contains a Ca-binding site that is allosterically coupled to the…
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