FAQ

deoxyhypusine synthase

Known as: DHS, DHPS, EC 2.5.1.46 
Deoxyhypusine synthase (369 aa, ~41 kDa) is encoded by the human DHPS gene. This protein plays a role in the synthesis of deoxyhypusine and the post… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1954-2017
051019542016

Related topics

Related topics

9 relations
Amino Acid BiosynthesisDHPS geneDPYS geneEnzyme Gene
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Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
deoxyhypusine synthase
Homo sapiens
protein metabolism
Post-Translational Protein Processing
DHPS gene
DPYS gene

Papers overview

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2013
2013
Allosteric Activation of Trypanosomatid Deoxyhypusine Synthase by a Catalytically Dead Paralog*♦
Polyamine biosynthesis is a key drug target in African trypanosomes. The "resurrection drug" eflornithine… (More)
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Highly Cited
2008
Highly Cited
2008
Interaction of the glucocorticoid receptor with the chromatin landscape.
The generality and spectrum of chromatin-remodeling requirements for nuclear receptor function are unknown. We have characterized… (More)
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2003
2003
Reversal of the deoxyhypusine synthesis reaction. Generation of spermidine or homospermidine from deoxyhypusine by deoxyhypusine synthase.
Deoxyhypusine synthase catalyzes the first step in hypusine (N epsilon-(4-amino-2-hydroxybutyl)lysine) synthesis in a single… (More)
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2003
2003
Induction of apoptosis by sphingoid long-chain bases in Aspergillus nidulans.
Sphingolipid metabolism is implicated to play an important role in apoptosis. Here we show that dihydrosphingosine (DHS) and… (More)
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Highly Cited
2002
Highly Cited
2002
The plant disease resistance gene Asc-1 prevents disruption of sphingolipid metabolism during AAL-toxin-induced programmed cell death.
The nectrotrophic fungus Alternaria alternata f.sp. lycopersici infects tomato plants of the genotype asc/asc by utilizing a host… (More)
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1995
1995
Deoxyhypusine synthase from rat testis: purification and characterization.
Deoxyhypusine synthase is the first enzyme involved in the post-translational formation of hypusine, a unique amino acid that… (More)
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1995
1995
Molecular cloning and functional expression of Neurospora deoxyhypusine synthase cDNA and identification of yeast deoxyhypusine synthase cDNA.
Deoxyhypusine synthase catalyzes the formation of deoxyhypusine residue on the eIF-5A precursor using spermidine as the substrate… (More)
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Highly Cited
1994
Highly Cited
1994
Primary structure and expression of the dihydropteroate synthetase gene of Plasmodium falciparum.
The enzyme dihydropteroate synthetase (DHPS) from Plasmodium falciparum is involved in the mechanism of action of the sulfone… (More)
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1992
1992
Cloning, sequencing, and enhanced expression of the dihydropteroate synthase gene of Escherichia coli MC4100.
The Escherichia coli gene coding for dihydropteroate synthase (DHPS) has been cloned and sequenced. The protein has 282 amino… (More)
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1989
1989
Interactions of metal ions with phosphatidylserine bilayer membranes: effect of hydrocarbon chain unsaturation.
A combination of surface monolayer, scanning calorimetry, 31P NMR, and spin-label ESR techniques has been used to monitor the… (More)
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