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deoxyhypusine synthase

Known as: DHS, DHPS, EC 2.5.1.46 
Deoxyhypusine synthase (369 aa, ~41 kDa) is encoded by the human DHPS gene. This protein plays a role in the synthesis of deoxyhypusine and the post… 
National Institutes of Health

Related topics

Related topics

10 relations
Amino Acid BiosynthesisDHPS geneDPYS geneEnzyme Gene

Broader (1)

Oxidoreductases Acting on CH-NH Group Donors

Papers overview

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2018
2018
Structural basis for the hepatoprotective effects of antihypertensive 1,4-dihydropyridine drugs.
2015
2015
Molecular simulations study of novel 1,4‐dihydropyridines derivatives with a high selectivity for Cav3.1 calcium channel
1,4‐Dihydropyridines (DHPs) have been developed to treat hypertension, angina, and nerve system disease. They are thought to… 
2010
2010
Latent enamine functionality of 5-methyl-2,3-dihydropyrazines.
Tautomerization of methyl-substituted dihydropyrazine (DHP) derivatives to their latent enamine form was investigated… 
2009
2009
Probing the roles of non-homologous insertions in the N-terminal domain of Plasmodium falciparum hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase.
2009
2009
Evolution of pyrrolizidine alkaloids in Phalaenopsis orchids and other monocotyledons: identification of deoxyhypusine synthase, homospermidine synthase and related pseudogenes.
2008
2008
Biochemical Control Aspects in Lignin Polymerization
Lignins are produced by all vascular plants and they represent one of the most abundant groups of biopolymers in nature. Lignin… 
2004
2004
Molecular Cloning of Bovine eIF5A and Deoxyhypusine Synthase cDNA
Deoxyhypusine synthase is the first of the two enzymes that catalyzes the maturation of eukaryotic initiation factor 5A (eIF5A… 
1997
1997
Enzyme-Substrate Intermediate at a Specific Lysine Residue Is Required for Deoxyhypusine Synthesis
Deoxyhypusine synthase catalyzes the first step in the post-translational synthesis of hypusine [Nε-(4-amino-2-hydroxybutyl… 
1997
1997
Biochemical and immunological characterization of deoxyhypusine synthase purified from the yeast Saccharomyces carlsbergensis.
Deoxyhypusine synthase catalyzes the NAD+-dependent formation of deoxyhypusine in the eIF-5A precursor protein by transferring… 
1991
1991
Direct genetic selection of a maize cDNA for dihydrodipicolinate synthase in an Escherichia coli dapA−auxotroph
SummaryDihydrodipicolinate synthase (DHPS; EC 4.2.1.52) is the first committed enzyme in the lysine branch of the aspartate… 
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