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DHPS gene

Known as: migration-inducing gene 13, DHPS, Deoxyhypusine Synthase Gene 
This gene plays a role in cell proliferation and protein synthesis.
National Institutes of Health

Related topics

Related topics

8 relations
Amino Acid BiosynthesisDPYS genePost-Translational Protein Processingdeoxyhypusine synthase

Broader (1)

Genes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Evolution of pyrrolizidine alkaloids in Phalaenopsis orchids and other monocotyledons: identification of deoxyhypusine synthase, homospermidine synthase and related pseudogenes.
Highly Cited
2007
Highly Cited
2007
Role of Hypusinated Eukaryotic Translation Initiation Factor 5A in Polyamine Depletion-induced Cytostasis*
We have earlier shown that α-methylated spermidine and spermine analogues rescue cells from polyamine depletion-induced growth… 
2004
2004
Horizontal gene transfer and archaeal origin of deoxyhypusine synthase homologous genes in bacteria.
Highly Cited
2003
Highly Cited
2003
Reversal of the Deoxyhypusine Synthesis Reaction
Deoxyhypusine synthase catalyzes the first step in hypusine (Nϵ-(4-amino-2-hydroxybutyl)lysine) synthesis in a single cellular… 
Highly Cited
2003
Highly Cited
2003
Molecular Evolution by Change of Function
Deoxyhypusine synthase participates in the post-translational activation of the eukaryotic initiation factor 5A (eIF5A). The… 
1997
1997
Enzyme-Substrate Intermediate Formation at Lysine 329 of Human Deoxyhypusine Synthase*
Deoxyhypusine (N ε-(4-aminobutyl)lysine) is the key intermediate in the posttranslational synthesis of the unique amino acid… 
1997
1997
Enzyme-Substrate Intermediate at a Specific Lysine Residue Is Required for Deoxyhypusine Synthesis
Deoxyhypusine synthase catalyzes the first step in the post-translational synthesis of hypusine [Nε-(4-amino-2-hydroxybutyl… 
Highly Cited
1996
Highly Cited
1996
Deoxyhypusine synthase gene is essential for cell viability in the yeast Saccharomyces cerevisiae
1995
1995
Identification of YHR068w in Saccharomyces cerevisiae Chromosome VIII as a Gene for Deoxyhypusine Synthase
Deoxyhypusine synthase catalyzes the formation of deoxyhypusine, the first step in hypusine biosynthesis. Amino acid sequences of… 
1995
1995
Purification of Deoxyhypusine Synthase from Neurospora crassa to Homogeneity by Substrate Elution Affinity Chromatography (*)
Deoxyhypusine synthase is an NAD-dependent enzyme that catalyzes the formation of deoxyhypusine residue on the eIF-5A precursor… 
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