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deoxycytidine kinase activity

Known as: NTP:deoxycytidine 5'-phosphotransferase activity, Ara-C kinase activity, deoxycytidine-cytidine kinase activity 
Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP. [EC:2.7.1.74]
National Institutes of Health

Papers overview

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2011
2011
Cladribine (2-chloro-2'-deoxyadenosine) is a purine nucleoside analogue (PNA) which causes targeted and sustained reduction of… 
2005
2005
Objective:To evaluate whether an inter-individual variability in the activity of thymidine kinase (TK) and deoxycytidine kinase… 
2000
2000
In contrast to deoxycytidine kinase from leukemic blasts7, the recombinant dCK is a poor substrate for protein kinase C. Protein… 
Highly Cited
1999
Highly Cited
1999
Deoxycytidine kinase (dCK), one of the rate-limiting enzymes in the intracellular metabolism of many antileukaemic drugs, was… 
1993
1993
Deoxycytidine kinase activity (dCk) was monitored in cell lines from a rat acute myeloid leukemia model of acquired resistance to… 
1993
1993
(1) Deoxycytidine kinase activity increased in a transformation- and progression-linked fashion in rat hepatomas of different… 
1992
1992
The activity of deoxycytidine kinase (EC 2.7.1.74), an important pyrimidine salvage enzyme, was elevated 5- to 30-fold in human… 
1989
1989
  • B. Ullman
  • Advances in experimental medicine and biology
  • 1989
  • Corpus ID: 43261136
The growth inhibitory effects and metabolism of 2',3'-dideoxycytidine (ddC) were examined in wild type human CEM T lymphoblasts… 
Highly Cited
1988
Highly Cited
1988
In order to analyze the cellular determinants that mediate the action of 2',3'-dideoxycytidine, the growth inhibitory and… 
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Highly Cited
1974
Highly Cited
1974
Summary Genetical and biochemical evidence indicates that herpes simplex virus (types 1 and 2) specifies a unique kinase activity… 
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