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deoxycytidine kinase activity
Known as:
NTP:deoxycytidine 5'-phosphotransferase activity
, Ara-C kinase activity
, deoxycytidine-cytidine kinase activity
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Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP. [EC:2.7.1.74]
National Institutes of Health
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Deoxycytidine Kinase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Influence of Phosphorylation of THR-3, SER-11, and SER-15 on Deoxycytidine Kinase Activity and Stability
C. Smal
,
S. Ntamashimikiro
,
A. Arts
,
E. Van Den Neste
,
F. Bontemps
Nucleosides, Nucleotides & Nucleic Acids
2010
Corpus ID: 38414422
Deoxycytidine kinase (dCK) is a key enzyme in the salvage of deoxyribonucleosides and in the activation of several anticancer and…
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1993
1993
Regulation of deoxycytidine kinase activity and inhibition by DFDC.
G. Weber
,
R. L. Singhal
,
+5 authors
K. Look
Advances in Enzyme Regulation
1993
Corpus ID: 2737002
1992
1992
Increased deoxycytidine kinase activity in cancer cells and inhibition by difluorodeoxycytidine.
R. L. Singhal
,
Y. Yeh
,
T. Szekeres
,
G. Weber
Oncology Research
1992
Corpus ID: 44263481
The activity of deoxycytidine kinase (EC 2.7.1.74), an important pyrimidine salvage enzyme, was elevated 5- to 30-fold in human…
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1989
1989
Dideoxycytidine metabolism in wild type and mutant CEM cells deficient in nucleoside transport or deoxycytidine kinase.
B. Ullman
Advances in Experimental Medicine and Biology
1989
Corpus ID: 43261136
The growth inhibitory effects and metabolism of 2',3'-dideoxycytidine (ddC) were examined in wild type human CEM T lymphoblasts…
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1989
1989
Development of resistance to 1-beta-D-arabinofuranosylcytosine after high-dose treatment in childhood lymphoblastic leukemia: analysis of resistance mechanism in established cell lines.
U. Kees
,
J. Ford
,
V. M. Dawson
,
E. Piall
,
G. Aherne
Cancer Research
1989
Corpus ID: 25904288
Cell lines PER-163 and PER-164 are derived from a patient with acute lymphoblastic leukemia who developed resistance to 1-beta-D…
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1987
1987
High degree of resistance to 5-aza-2'-deoxycytidine in L1210 cells in vitro associated with almost complete loss of deoxycytidine kinase activity.
J. Veselý
Neoplasma (Bratislava)
1987
Corpus ID: 25421869
In L1210 mouse leukemic cells the resistance towards 5-aza-2'-deoxycytidine was developed in vitro by stepwise selection in…
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1985
1985
1-beta-D-arabinofuranosylcytosine metabolism and incorporation into DNA as determinants of in vivo murine tumor cell response.
C. Riva
,
Y. Rustum
Cancer Research
1985
Corpus ID: 20596615
In this study, 1-beta-D-arabinofuranosylcytosine 5'-triphosphate (ara-CTP) formation, retention, and incorporation into DNA were…
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1980
1980
The induction and characterization of mouse lymphoma L5178Y cell lines resistant to 1-beta-d-arabinofuranosylcytosine.
A. M. Rogers
,
R. Hill
,
A. Lehmann
,
C. Arlett
,
V. W. Burns
Mutation research
1980
Corpus ID: 24899694
1973
1973
Demonstration of a deoxycytidine kinase activity in extracts of Bacillus megaterium KM.
J. T. Wachsman
,
D. Morgan
Applied microbiology
1973
Corpus ID: 41911502
Extracts of Bacillus megaterium KM have been shown to possess a deoxycytidine kinase activity which functions optimally with…
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1968
1968
Studies on the mode of action of the copper(II)chelate of 2-keto-3-ethoxybutyraldehyde-bis(thiosemicarbazone).
B. Bhuyan
,
T. Betz
Cancer Research
1968
Corpus ID: 34213217
Summary Among 2-keto-3-ethoxybutyraldehyde-bis(thiosemicarbazone) (KTS) and its metal chelates, Cu(II)KTS was selected for…
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