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deoxycytidine kinase activity
Known as:
NTP:deoxycytidine 5'-phosphotransferase activity
, Ara-C kinase activity
, deoxycytidine-cytidine kinase activity
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Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP. [EC:2.7.1.74]
National Institutes of Health
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Deoxycytidine Kinase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Thymidine kinase and deoxycytidine kinase activity in mononuclear cells from antiretroviral-naive HIV-infected patients
O. Turriziani
,
O. Butera
,
+7 authors
G. Antonelli
AIDS (London)
2005
Corpus ID: 12801931
Objective:To evaluate whether an inter-individual variability in the activity of thymidine kinase (TK) and deoxycytidine kinase…
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2001
2001
Steroids affect collateral sensitivity to gemcitabine of multidrug-resistant human lung cancer cells.
A. Bergman
,
H. Pinedo
,
G. Peters
European Journal of Pharmacology
2001
Corpus ID: 23049112
2000
2000
Effect of phosphorylation on deoxycytidine kinase activity.
T. Spasokoukotskaja
,
Z. Csapó
,
+4 authors
M. Staub
Advances in Experimental Medicine and Biology
2000
Corpus ID: 36779524
In contrast to deoxycytidine kinase from leukemic blasts7, the recombinant dCK is a poor substrate for protein kinase C. Protein…
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1993
1993
Role of deoxycytidine kinase in an in vitro model for AraC- and DAC-resistance: substrate-enzyme interactions with deoxycytidine, 1-beta-D-arabinofuranosylcytosine and 5-aza-2'-deoxycytidine.
A. Stegmann
,
M. Honders
,
M. Kester
,
J. Landegent
,
R. Willemze
Leukemia
1993
Corpus ID: 30551376
Deoxycytidine kinase activity (dCk) was monitored in cell lines from a rat acute myeloid leukemia model of acquired resistance to…
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1992
1992
Increased deoxycytidine kinase activity in cancer cells and inhibition by difluorodeoxycytidine.
R. L. Singhal
,
Y. Yeh
,
T. Szekeres
,
G. Weber
Oncology Research
1992
Corpus ID: 44263481
The activity of deoxycytidine kinase (EC 2.7.1.74), an important pyrimidine salvage enzyme, was elevated 5- to 30-fold in human…
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1989
1989
Dideoxycytidine metabolism in wild type and mutant CEM cells deficient in nucleoside transport or deoxycytidine kinase.
B. Ullman
Advances in Experimental Medicine and Biology
1989
Corpus ID: 43261136
The growth inhibitory effects and metabolism of 2',3'-dideoxycytidine (ddC) were examined in wild type human CEM T lymphoblasts…
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1989
1989
Development of resistance to 1-beta-D-arabinofuranosylcytosine after high-dose treatment in childhood lymphoblastic leukemia: analysis of resistance mechanism in established cell lines.
U. Kees
,
J. Ford
,
V. M. Dawson
,
E. Piall
,
G. Aherne
Cancer Research
1989
Corpus ID: 25904288
Cell lines PER-163 and PER-164 are derived from a patient with acute lymphoblastic leukemia who developed resistance to 1-beta-D…
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Highly Cited
1988
Highly Cited
1988
Genetic analysis of 2',3'-dideoxycytidine incorporation into cultured human T lymphoblasts.
B. Ullman
,
T. Coons
,
S. Rockwell
,
K. McCartan
Journal of Biological Chemistry
1988
Corpus ID: 2272535
1980
1980
The induction and characterization of mouse lymphoma L5178Y cell lines resistant to 1-beta-d-arabinofuranosylcytosine.
A. M. Rogers
,
R. Hill
,
A. Lehmann
,
C. Arlett
,
V. W. Burns
Mutation research
1980
Corpus ID: 24899694
Highly Cited
1974
Highly Cited
1974
Induction of both thymidine and deoxycytidine kinase activity by herpes viruses.
A. T. Jamieson
,
G. Gentry
,
J. Subak-Sharpe
Journal of General Virology
1974
Corpus ID: 12993608
Summary Genetical and biochemical evidence indicates that herpes simplex virus (types 1 and 2) specifies a unique kinase activity…
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