dendritic spine morphogenesis
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The high resolution structure of the cytoskeleton in dendritic spines and their precursors, dendritic filopodia, was… Expand The microRNA pathway has been implicated in the regulation of synaptic protein synthesis and ultimately in dendritic spine… Expand Dendritic spines are the postsynaptic receptive regions of most excitatory synapses, and their morphological plasticity play a… Expand PAR-3 (partitioning-defective gene 3) is essential for cell polarization in many contexts, including axon specification. However… Expand The small GTPases Rac1 and Cdc42 are key regulators of the morphogenesis of actin-rich dendritic spines in neurons. However… Expand The morphogenesis of dendritic spines, the major sites of excitatory synaptic transmission in the brain, is important in synaptic… Expand The postsynaptic density (PSD) proteins Shank and Homer cooperate to induce the maturation and enlargement of dendritic spines… Expand The number and shape of dendritic spines are influenced by activity and regulated by molecules that organize the actin… Expand Synaptic remodeling has been postulated as a mechanism underlying synaptic plasticity, and cadherin adhesion molecules are… Expand We previously reported that the cell surface proteoglycan syndecan-2 can induce dendritic spine formation in hippocampal neurons… Expand