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dendritic spine morphogenesis

The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
The high resolution structure of the cytoskeleton in dendritic spines and their precursors, dendritic filopodia, was… Expand
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Highly Cited
2009
Highly Cited
2009
The microRNA pathway has been implicated in the regulation of synaptic protein synthesis and ultimately in dendritic spine… Expand
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Highly Cited
2006
Highly Cited
2006
PAR-3 (partitioning-defective gene 3) is essential for cell polarization in many contexts, including axon specification. However… Expand
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Highly Cited
2005
Highly Cited
2005
The small GTPases Rac1 and Cdc42 are key regulators of the morphogenesis of actin-rich dendritic spines in neurons. However… Expand
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Highly Cited
2003
Highly Cited
2003
The morphogenesis of dendritic spines, the major sites of excitatory synaptic transmission in the brain, is important in synaptic… Expand
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Highly Cited
2003
Highly Cited
2003
The postsynaptic density (PSD) proteins Shank and Homer cooperate to induce the maturation and enlargement of dendritic spines… Expand
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Highly Cited
2003
Highly Cited
2003
Dendritic spines have two major structural elements: postsynaptic densities (PSDs) and actin cytoskeletons. PSD proteins are… Expand
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Highly Cited
2003
Highly Cited
2003
The number and shape of dendritic spines are influenced by activity and regulated by molecules that organize the actin… Expand
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Highly Cited
2002
Highly Cited
2002
Synaptic remodeling has been postulated as a mechanism underlying synaptic plasticity, and cadherin adhesion molecules are… Expand
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Highly Cited
2001
Highly Cited
2001
We previously reported that the cell surface proteoglycan syndecan-2 can induce dendritic spine formation in hippocampal neurons… Expand
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