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deltaline

 
National Institutes of Health

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Diterpenes

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2013
2013
Effect of α₇ nicotinic acetylcholine receptor agonists and antagonists on motor function in mice.
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated cation channels found throughout the body, and serve to mediate… Expand
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2012
2012
Unusual Reactions of a 7,17-seco-type C19-Diterpenoid Alkaloid Derived from Deltaline
Treatment of a 7,17-seco-type C19-diterpenoid alkaloid (3), prepared from deltaline (8), with triethylamine in either DMF or TEG… Expand
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2011
2011
Comparison of the toxic effects of two duncecap larkspur (Delphinium occidentale) chemotypes in mice and cattle.
OBJECTIVE To compare the toxic effects of a Delphinium occidentale chemotype containing N-(methylsuccinimido… Expand
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2011
2011
A toxicokinetic comparison of norditerpenoid alkaloids from Delphinium barbeyi and D. glaucescens in cattle.
Cattle are poisoned by N-(methylsuccinimido) anthranoyllycoctonine type (MSAL-type) and 7,8-methylenedioxylycoctonine type (MDL… Expand
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2009
2009
Serum elimination profiles of methyllycaconitine and deltaline in cattle following oral administration of larkspur (Delphinium barbeyi)
 
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2008
2008
The effect of 7,8-methylenedioxylycoctonine-type diterpenoid alkaloids on the toxicity of methyllycaconitine in mice.
Larkspur plants contain numerous norditerpenoid alkaloids, which include the 7,8-methylenedioxylycoctonine (MDL)-type alkaloids… Expand
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1999
1999
Analysis of toxic norditerpenoid alkaloids in Delphinium species by electrospray, atmospheric pressure chemical ionization, and sequential tandem mass spectrometry.
A rapid electrospray mass spectrometry method was developed for screening larkspur (Delphinium spp.) plant material for toxic… Expand
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1999
1999
Effects of Delphinium alkaloids on neuromuscular transmission.
The Delphinium alkaloids methyllycaconitine (MLA), nudicauline, 14-deacetylnudicauline (14-DN), barbinine, and deltaline were… Expand
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1996
1996
Nudicauline and elatine as potent norditerpenoid ligands at rat neuronal alpha-bungarotoxin binding sites: importance of the 2-(methylsuccinimido)benzoyl moiety for neuronal nicotinic acetylcholine…
Methyllycaconitine (MLA, 1) is a novel, potent probe for mammalian and insect nicotinic acetylcholine receptors (nAChR) and… Expand
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1992
1992
Larkspur chemistry: toxic alkaloids ln tall larkspurs.
Paper presented at the "Symposium on Ingestion of Poisonous Plants by Livestock," February 15, 1990, Reno, Nevada. 
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