deguelin

Known as: (7aS-cis)-13,13a-Dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(7aH)-one, 13,13a-dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis(1)benzopyrano(3,4-b:6',5'-e)pyran-7(7aH)-one 
 
National Institutes of Health

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2008
2008
Hypoxia-inducible factor 1 (HIF-1) plays an essential role in tumor angiogenesis and growth by regulating the transcription of… (More)
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2008
2008
Deguelin is a rotenoid isolated from several plant species, which has been reported to have chemopreventive effects in skin… (More)
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2008
2008
Retinal neovascularization is the most common cause of blindness; Retinopathy of pre-maturity (ROP) for children and diabetic… (More)
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2007
2007
BACKGROUND The molecular chaperone heat shock protein 90 (Hsp90) participates in preserving the expression and activity of… (More)
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2007
2007
Several natural compounds, especially plant products and dietary constituents, are able to exhibit 'angiopreventive' (anti… (More)
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Highly Cited
2005
Highly Cited
2005
Tobacco carcinogens induce Akt activation and lung carcinogenesis. We previously demonstrated that deguelin, a natural plant… (More)
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2004
2004
The increased expression of cyclooxygenase (COX)-2 significantly enhances carcinogenesis and inflammatory reactions, and its… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Because lung cancer is the leading cause of cancer-related death, new approaches for preventing and controlling the… (More)
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2001
2001
Purpose: To study the pharmacokinetics of deguelin, a naturally occurring potential cancer chemopreventive agent, in rats… (More)
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Highly Cited
1997
Highly Cited
1997
Deguelin, a natural product isolated from Mundulea sericea (Leguminosae), was shown previously to mediate strong inhibition of 12… (More)
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