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db/db Mouse

Known as: db/db 
The diabetic mutant mouse was derived from a spontaneous mutation in a C57BL/K progenitor mouse at the Jackson Laboratory in 1966. The db/db mouse is… 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
In humans with nonalcoholic fatty liver, diabetes is associated with more advanced disease. We have previously shown that… 
Highly Cited
2007
Highly Cited
2007
To attain a profile of protein expression during diabetes, we applied proteomic analysis to glomeruli of 160-day-old db/db… 
Highly Cited
2005
Highly Cited
2005
Muraglitazar/BMS-298585 (2) has been identified as a non-thiazolidinedione PPAR alpha/gamma dual agonist that shows potent… 
Highly Cited
2005
Highly Cited
2005
INTRODUCTION Erectile dysfunction (ED) in diabetes is associated with autonomic neuropathy and endothelial dysfunction. Whereas… 
Highly Cited
2004
Highly Cited
2004
Insulin-induced gene 1 (INSIG-1) is a key regulator in the processing of the sterol regulatory element-binding proteins (SREBPs… 
Highly Cited
2003
Highly Cited
2003
Obesity plays a central role in the development of insulin resistance and type 2 diabetes. We therefore examined the effects of a… 
Highly Cited
2002
Highly Cited
2002
A novel nonthiazolidinedione dual peroxisome proliferator- activated receptor (PPAR)-alpha/gamma agonist, LY465608, was designed… 
Highly Cited
1999
Highly Cited
1999
Ciliary neurotrophic factor (CNTF) is a neurocytokine expressed in glial cells that acts on brain cells to promote gene… 
Highly Cited
1996
Highly Cited
1996
The obese gene product, leptin, is synthesized in adipose tissue and is a circulating factor regulating body weight. To identify…