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daurinol

National Institutes of Health

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BenzodioxolesNaphthalenes

Papers overview

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2016
2016
Abstract A23: Daurinol suppresses human cancer metastasis by inhibition of focal adhesion kinase (FAK) signaling pathways
Background and Purpose: Globally most of the cancers associated with mortality and morbidity arise from metastatic spread of… 
2016
2016
Daurinol, a cancer suppressing plant lignan with low hematological toxicity
2015
2015
Synthesis and anticancer activity of 4-aza-daurinol derivatives
Daurinol, a natural aryl naphthalene lactone, has been reported to have antiproliferative activity against various cell lines… 
2012
2012
Anti‐cancer effects of daurinol, a plant arynaphthalane lignan, with low hematological toxicity compared to etoposide
We investigated the cancer suppression effects of daurinol, a plant lignan from Haplophyllum dauricum, and their molecular… 
Highly Cited
2011
Highly Cited
2011
A novel topoisomerase inhibitor, daurinol, suppresses growth of HCT116 cells with low hematological toxicity compared to etoposide.
We report that daurinol, a novel arylnaphthalene lignan, is a promising potential anticancer agent with adverse effects that are… 
2007
2007
A pharmaceutical composition containing daurinol for the prevention and treatment of cancers
A composition comprising daurinol is provided to inhibit proliferation of cancer cells, disturb cell cycle by stopping an S… 
2004
2004
Use of double proton resonance to establish the structure of lignans of the arylnaphthalene series. The structure of daurinol
On the basis of the results of a study of PMR spectra with the use of double proton resonance, the promising nature of this… 
2004
2004
13C NMR spectra of arylnaphthalene lignans
The13C NMR spectra have been investigated of a number of arylnaphthalene lignans of plant origin: daurinol and its acetyl… 
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