cytotoxic T cell degranulation

Known as: cytotoxic T lymphocyte granule exocytosis, cytotoxic T lymphocyte degranulation, cytotoxic T-lymphocyte granule exocytosis 
The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell. [ISBN:0781735149]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2014
012319942014

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Dear Editor, Hemophagocytic lymphohistiocytosis (HLH) is a lifethreatening syndrome with exaggerated but ineffective immune… (More)
  • figure 1
  • table 1
Is this relevant?
2009
2009
Cytotoxic T cells (CTLs) and natural killer cells (NKs) both kill virus-infected cells and tumor cells by releasing the cytoxic… (More)
Is this relevant?
2009
2009
Cytotoxic T cells kill virus-infected cells and tumor cells by releasing lytic granules that contain cell-killing contents… (More)
Is this relevant?
2009
2009
Deficiency in acid sphingomyelinase causes lysosomal storage of sphingomyelin, mediates resistance to stress-induced apoptosis… (More)
  • figure 1
Is this relevant?
2008
2008
Cytotoxic T cells (CTLs) kill target cells by releasing lytic agents via regulated exocytosis. Three signals are known to be… (More)
Is this relevant?
2007
2007
We have tested the idea that calcineurin, a calcium-dependent phosphatase that is critical for activating cytokine gene… (More)
Is this relevant?
2005
2005
Cytotoxic T lymphocytes kill targets via secretion of lytic agents including perforin and granzymes. Recently, new methods have… (More)
Is this relevant?
2003
2003
CD8(+) cytotoxic T lymphocyte (CTL) clones are able to exert both perforin- and Fas-dependent cytotoxicity. We show in the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1994
1994
Phorbol myristate acetate (PMA) plus ionomycin induces the tyrosine phosphorylation of several cytotoxic T lymphocyte (CTL… (More)
Is this relevant?