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negative regulation of cytotoxic T cell degranulation

Known as: downregulation of cytotoxic T cell degranulation, negative regulation of cytotoxic T-cell granule exocytosis, negative regulation of cytotoxic T lymphocyte degranulation 
Any process that stops, prevents, or reduces the rate of cytotoxic T cell degranulation. [ISBN:0781735149]
National Institutes of Health

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Broader (1)

biological control
cytotoxic T cell degranulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
RETRACTED ARTICLE: Effect of NS-398, a cyclooxygenase-2 selective inhibitor, on the cytotoxicity of cytotoxic T lymphocytes to ovarian carcinoma cells
AbstractCyclooxygenase-2 (COX-2) is a key limited enzyme of prostaglandin (PG) synthesis and has been… 
2012
2012
CD40 triggering induces strong cytotoxic T lymphocyte responses to heat-killed Staphylococcus aureus immunization in mice: a new vaccine strategy for staphylococcal mastitis.
2006
2006
A novel PKC regulates ERK activation and degranulation of cytotoxic T lymphocytes: Plasticity in PKC regulation of ERK
Stimulation of cytotoxic T lymphocyte (CTL) degranulation with plate‐bound anti‐CD3 Ab leads to two phases of ERK activation: an… 
2005
2005
Evasion of cytotoxic T lymphocytes is a functional constraint maintaining HIV‐1 Nef expression
Nef expression is not required for HIV‐1 replication and is highly targeted by CD8+ CTL, raising the question of why Nef… 
2003
2003
Beta 1/beta 3 integrin ligation is uncoupled from ERK1/ERK2 activation in cytotoxic T lymphocytes.
beta 3 integrins mediate fibronectin binding and enhanced activation of cytotoxic T lymphocytes (CTL). The intracellular signals… 
2002
2002
Immunization with Chaperone-Peptide Complex Induces Low-Avidity Cytotoxic T Lymphocytes Providing Transient Protection against Herpes Simplex Virus Infection
ABSTRACT Heat shock proteins loaded with viral peptides were shown to induce a CD8+ T cell response and confer protective… 
1995
1995
Glycosylphosphatidylinositol‐linked Db does not induce an influenza‐specific cytotoxic T lymphocyte response or recycle membrane‐bound peptides
Major histocompatibility complex (MHC) class I molecules, as well as MHC class I‐bound peptides, are known to recycle between the… 
Highly Cited
1994
Highly Cited
1994
Contribution of lymphocyte function-associated-1/intercellular adhesion molecule-1 binding to the adhesion/signaling cascade of cytotoxic T lymphocyte activation
A rapid induction of adhesion to immobilized intercellular adhesion molecule (ICAM)-1 occurs when cytotoxic T lymphocytes (CTL… 
Highly Cited
1989
Highly Cited
1989
Free fatty acid perturbation of transmembrane signaling in cytotoxic T lymphocytes.
Transmembrane signaling in CTL is found to be extremely sensitive to short term exposure to long chain free fatty acids (FFA… 
Highly Cited
1979
Highly Cited
1979
The role of cyclic AMP in modulating cytotoxic T lymphocytes. I. In-vivo-generated cytotoxic lymphocytes, but not in vitro-generated cytotoxic lymphocytes, are inhibited by cyclic AMP-active agents.
Cytotoxic T lymphocytes (CTL) were generated in the spleen by immunizing C57BL/6 mice (H-2b) i.p. with allogeneic P815 cells (H… 
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