negative regulation of cytotoxic T cell degranulation

Known as: downregulation of cytotoxic T cell degranulation, negative regulation of cytotoxic T-cell granule exocytosis, negative regulation of cytotoxic T lymphocyte degranulation 
Any process that stops, prevents, or reduces the rate of cytotoxic T cell degranulation. [ISBN:0781735149]
National Institutes of Health

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Broader (1)

biological control
cytotoxic T cell degranulation

Papers overview

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2006
2006
A novel PKC regulates ERK activation and degranulation of cytotoxic T lymphocytes: Plasticity in PKC regulation of ERK.
Stimulation of cytotoxic T lymphocyte (CTL) degranulation with plate-bound anti-CD3 Ab leads to two phases of ERK activation: an… (More)
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Highly Cited
2005
Highly Cited
2005
Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes.
Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecules (ICAMs) facilitates T cell… (More)
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2005
2005
Intragranular vesiculotubular compartments are involved in piecemeal degranulation by activated human eosinophils.
Eosinophils, leukocytes involved in allergic, inflammatory and immunoregulatory responses, have a distinct capacity to rapidly… (More)
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2004
2004
Eosinophil degranulation in the allergic lung of mice primarily occurs in the airway lumen.
Eosinophil degranulation is thought to play a pivotal role in the pathogenesis of allergic disorders. Although mouse models of… (More)
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2002
2002
Surface Cytotoxic T Lymphocyte–associated Antigen 4 Partitions Within Lipid Rafts and Relocates to the Immunological Synapse under Conditions of Inhibition of T Cell Activation
T cell activation through the T cell receptor (TCR) involves partitioning of receptors into discrete membrane compartments known… (More)
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2000
2000
Piecemeal degranulation of peripheral blood eosinophils: a study of allergic subjects during and out of the pollen season.
The variability of serum and plasma levels of eosinophil granule proteins in different clinical conditions, interpreted as the… (More)
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Review
1999
Review
1999
Stress proteins and immunity mediated by cytotoxic T lymphocytes.
Chaperone molecules, including members of the heat shock protein family, are able to stimulate alphabeta and gammadelta T cells… (More)
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1995
1995
The effects of natural altered peptide ligands on the whole blood cytotoxic T lymphocyte response to human immunodeficiency virus.
Cytotoxic T lymphocytes (CTL) directed against human immunodeficiency virus (HIV)-1 are detectable in the majority of infected… (More)
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1993
1993
Role of cAMP in regulating cytotoxic T lymphocyte adhesion and motility.
We investigated the functional role of the cAMP pathway in human cytotoxic T lymphocyte (CTL)-target interaction. Pharmacological… (More)
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Highly Cited
1978
Highly Cited
1978
Transfer of specific cytotoxic T lymphocytes protects mice inoculated with influenza virus
THERE is remarkably little information about the possible importance of cell-mediated immune responses in the protection of hosts… (More)
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