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cytokine biosynthesis

Known as: cytokine biosynthetic process, cytokine synthesis, cytokine anabolism 
The chemical reactions and pathways resulting in the formation of cytokines, any of a group of proteins that function to control the survival, growth… 
National Institutes of Health

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Broader (1)

cytokine production
negative regulation of cytokine biosynthetic processpositive regulation of cytokine biosynthetic processregulation of cytokine biosynthetic process

Papers overview

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Highly Cited
2008
Highly Cited
2008
IL-33 mediates antigen-induced cutaneous and articular hypernociception in mice
IL-33, a new member of the IL-1 family, signals through its receptor ST2 and induces T helper 2 (Th2) cytokine synthesis and… 
Highly Cited
2004
Highly Cited
2004
Chronic graft-versus-host disease is associated with increased numbers of peripheral blood CD4+CD25high regulatory T cells.
Chronic graft-versus-host disease (cGVHD) is characterized by a state of profound immunodeficiency in association with… 
Highly Cited
2002
Highly Cited
2002
B7-H1 Is Expressed by Human Endothelial Cells and Suppresses T Cell Cytokine Synthesis1
Human endothelial cells (ECs) provide costimulatory signals sufficient to activate resting memory T cells to produce IL-2 and IFN… 
Highly Cited
2001
Highly Cited
2001
Cytokine production by mouse myeloid dendritic cells in relation to differentiation and terminal maturation induced by lipopolysaccharide or CD40 ligation.
Although it is known that dendritic cells (DCs) produce cytokines, there is little information about how cytokine synthesis is… 
Highly Cited
2000
Highly Cited
2000
Activated and Memory CD8+ T Cells Can Be Distinguished by Their Cytokine Profiles and Phenotypic Markers1
Dissecting the mechanisms of T cell-mediated immunity requires the identification of functional characteristics and surface… 
Highly Cited
1999
Highly Cited
1999
Immunization with α‐galactosylceramide polarizes CD1‐reactive NK T cells towards Th2 cytokine synthesis
We have compared the immune responses of mice immunized either with α‐galactosylceramide (α‐GalCer), capable of eliciting a CD1… 
Highly Cited
1995
Highly Cited
1995
Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations
CD4+ T helper (Th) cells can be classified into different types based on their cytokine profile. Cells with these polarized… 
Highly Cited
1991
Highly Cited
1991
Production of IL-10 by CD4+ T lymphocytes correlates with down-regulation of Th1 cytokine synthesis in helminth infection.
After the onset of parasite egg deposition, mice infected with the helminth Schistosoma mansoni mount strong Th2 cytokine… 
Highly Cited
1991
Highly Cited
1991
Expression of granulocyte‐macrophage colony‐stimulating factor in rheumatoid arthritis: Regulation by tumor necrosis factor‐α
Granulocyte‐macrophage colony‐stimulating factor (GM‐CSF), in addition to being a growth factor for granulocytes and macrophages… 
Highly Cited
1990
Highly Cited
1990
Isolation of monoclonal antibodies specific for IL-4, IL-5, IL-6, and a new Th2-specific cytokine (IL-10), cytokine synthesis inhibitory factor, by using a solid phase radioimmunoadsorbent assay.
Hybridomas were produced from a rat that was immunized with partially purified proteins from supernatants of induced Th2 cells… 
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