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cytisine

Known as: 1,2,3,4,5,6-hexahydro-1,5-methano-8H- pyrido(1,2-a)(1,5)diazocin-8-one, (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido[1,2a][1,5]diazocin-8-one, Ulexin 
National Institutes of Health

Related topics

Related topics

8 relations
3-hydroxy-11-norcytisineCYTISINE 8 mg in 1 mg ORAL STRIP [TBX-Free]

Broader (3)

AlkaloidsAzocinesQuinolizines

Narrower (3)

Tabexcytisine dihydrochloride, trihydratecytisine hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
The neuronal nicotinic α4β2 receptor has a high maximal probability of being open
Background and purpose:  A fundamental property of transmitter‐gated ion channels is the probability a channel will be open… 
Highly Cited
2009
Highly Cited
2009
Nicotinic receptor agonists and antagonists increase sAPPα secretion and decrease Aβ levels in vitro
2009
2009
Synthesis, binding, and modeling studies of new cytisine derivatives, as ligands for neuronal nicotinic acetylcholine receptor subtypes.
The availability of drug affecting neuronal nicotinic acetylcholine receptors (nAChRs) may have important therapeutic potential… 
2007
2007
Gene targeting demonstrates that α4 nicotinic acetylcholine receptor subunits contribute to expression of diverse [3H]epibatidine binding sites and components of biphasic 86Rb+ efflux with high and…
Review
2005
Review
2005
From ligand design to therapeutic efficacy: the challenge for nicotinic receptor research.
Highly Cited
2004
Highly Cited
2004
Subsets of acetylcholine-stimulated 86Rb+ efflux and [125I]-epibatidine binding sites in C57BL/6 mouse brain are differentially affected by chronic nicotine treatment
2004
2004
Subsets of acetylcholine-stimulated 86Rb+ efflux and [125I]-epibatidine binding sites in C57BL/6 mouse brain are differentially affected by chronic nicotine treatment.
Highly Cited
2000
Highly Cited
2000
Total synthesis of (+/-)-cytisine via the intramolecular heck cyclization of activated N-alkyl glutarimides.
[reaction:see text] A synthesis of racemic cytisine 1 has been developed utilizing an intramolecular Heck cyclization to prepare… 
1998
1998
Binding thermodynamics at the human neuronal nicotine receptor.
Highly Cited
1984
Highly Cited
1984
Nature of nicotine binding to rat brain P2 fraction
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