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cyprodime

Known as: N-(cyclopropylmethyl)-4,14-dimethoxymorphinan-6-one 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Morphinans

Narrower (1)

cyprodime hydrobromide

Papers overview

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2003
2003
Involvement of the kappa-opioid receptor in the anxiogenic-like effect of CP 55,940 in male rats.
We have studied the possible interaction between three selective opioid-receptor antagonists, nor-binaltorphimine (NB: kappa) (5… 
2000
2000
The role of opioid receptors in hypoxic preconditioning against seizures in brain
2000
2000
Receptor binding and G-protein activation by new Met5-enkephalin-Arg6-Phe7 derived peptides.
1998
1998
Inhibitory effect of endomorphin-1 and -2 on acetylcholine release from myenteric plexus of guinea pig ileum.
Endomorphin-1 and -2, putative endogenous ligands for the mu-opioid receptor, inhibited acetylcholine (ACh) release evoked by… 
1997
1997
Characterization of opiate binding sites on the goldfish (Carassius auratus L.) pronephric leukocytes.
The head kidney is the main lymphopoietic organ of teleost fish. It is the source of leukocytes inhabiting the peritoneal cavity… 
1996
1996
Mu and kappa opioid system interactions in the expression of acute opioid dependence in isolated guinea-pig ileum
1996
1996
mu- and kappa-opioids inhibit K+ evoked glutamate release from rat cerebrocortical slices.
We have examined the effects of a range of opioid receptor subtype selective agonists on K+ evoked glutamate release from… 
1995
1995
Tonic modulation of neurotransmitter release in the guinea-pig myenteric plexus: effect of μ and κ opioid receptor blockade and of chronic sympathetic denervation
1990
1990
Synthesis and biological evaluation of 14-alkoxymorphinans. 3. Extensive study on cyprodime-related compounds.
A series of cyprodime-related compounds (2, 4-12, and 26) has been synthesized and evaluated for opioid agonist and antagonist… 
Highly Cited
1989
Highly Cited
1989
Synthesis and biological evaluation of 14-alkoxymorphinans. 2. (-)-N-(cyclopropylmethyl)-4,14-dimethoxymorphinan-6-one, a selective mu opioid receptor antagonist.
(-)-N-(Cyclopropylmethyl)-4,14-dimethoxymorphinan-6-one (2) was synthesized with 4,14-dimethoxy-N-methylmorphinan-6-one (1) as… 
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