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cymserine

National Institutes of Health

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2 relations

Broader (1)

Physostigmine
analogs & derivatives

Papers overview

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Review
2016
Review
2016
Multiple Targets for the Management of Alzheimer's Disease.
AD is a progressive and irreversible neurodegenerative disease and the most common cause of dementia in the elderly population… 
2014
2014
Prediction of comparative inhibition efficiency for a novel natural ligand, galangin against human brain acetylcholinesterase, butyrylcholinesterase and 5-lipoxygenase: a neuroinformatics study.
The present study elucidates molecular interactions of human acetylcholinesterase (AChE), butyrylcholinesterase (BuChE) and 5… 
2013
2013
Molecular interaction study of N1-p-fluorobenzyl-cymserine with TNF-α , p38 kinase and JNK kinase.
Alzheimer's disease (AD) is an age-related neurodegenerative disease distinguished by progressive memory loss and cognitive… 
2006
2006
Kinetics of human serum butyrylcholinesterase and its inhibition by a novel experimental Alzheimer therapeutic, bisnorcymserine.
An explosion in the incidence of neurodegenerative diseases, particularly Alzheimer's disease (AD), is predicted in coming… 
2006
2006
Kinetic analysis of the inhibition of human butyrylcholinesterase with cymserine.
2005
2005
Intravenous butyrylcholinesterase administration and plasma and brain levels of cocaine and metabolites in rats.
Highly Cited
2000
Highly Cited
2000
Cholinesterase inhibitors, β‐amyloid precursor protein and amyloid β‐peptides in Alzheimer's disease
The extracellular deposition of amyloid beta‐peptide (Aβ) in the form of cerebrovascular amyloid and extracellular plaques is one… 
2000
2000
Cholinesterase inhibitors, beta-amyloid precursor protein and amyloid beta-peptides in Alzheimer's disease.
The extracellular deposition of amyloid beta-peptide (Abeta) in the form of cerebrovascular amyloid and extracellular plaques is… 
Highly Cited
1999
Highly Cited
1999
Synthesis of novel phenserine-based-selective inhibitors of butyrylcholinesterase for Alzheimer's disease.
Four novel analogues (8-11) of cymserine (2) were synthesized by methods similar to those recently developed for the total… 
Review
1995
Review
1995
Phenserine and ring C hetero‐analogues: Drug candidates for the treatment of Alzheimer's disease
I . Historical Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11. Target of… 
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