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cyclocreatine

Known as: 1-carboxymethyl-2-iminoimidazolidine 
National Institutes of Health

Related topics

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3 relations

Broader (2)

Antineoplastic AgentsCreatinine
analogs & derivatives

Papers overview

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2015
2015
Submembranous recruitment of creatine kinase B supports formation of dynamic actin-based protrusions of macrophages and relies on its C-terminal flexible loop.
2001
2001
Hodgkin disease‐derived cell lines expressing ubiquitous mitochondrial creatine kinase show growth inhibition by cyclocreatine treatment independent of apoptosis
Ubiquitous mitochondrial creatine kinase (uMtCK), a key enzyme in energy metabolism, was identified by differential display PCR… 
2000
2000
Effects of cyclocreatine in rat hepatocarcinogenesis model.
Cyclocreatine (CCr), a substrate analogue of creatine kinase (CK: EC 2.7.3.2.), exhibits anti-tumor activity in vitro and in vivo… 
1998
1998
Cyclocreatine inhibits stimulated motility in tumor cells possessing creatine kinase
Cyclocreatine (1‐carboxymethyl‐2‐iminoimidazolidine), an analog of creatine and a substrate for creatine kinase (EC 2.7.3.2… 
1995
1995
Cyclocreatine accumulation leads to cellular swelling in C6 glioma multicellular spheroids: diffusion and one-dimensional chemical shift nuclear magnetic resonance microscopy.
Cyclocreatine, an analogue of creatine, inhibits tumor cell proliferation in vitro and in vivo. The effects of cyclocreatine in… 
1994
1994
Cell cycle studies of cyclocreatine, a new anticancer agent.
Cyclocreatine (CCr), a substrate analogue of creatine kinase (CK), exhibits antitumor activity in vitro and in vivo. To address… 
Highly Cited
1992
Highly Cited
1992
High-performance liquid chromatographic assays for free and phosphorylated derivatives of the creatine analogues beta-guanidopropionic acid and 1-carboxy-methyl-2-iminoimidazolidine (cyclocreatine).
1990
1990
Free ADP levels in transgenic mouse liver expressing creatine kinase. Effects of enzyme activity, phosphagen type, and substrate concentration.
1985
1985
Relative abilities of phosphagens with different thermodynamic or kinetic properties to help sustain ATP and total adenylate pools in heart during ischemia.
1983
1983
Synthesis and accumulation of an extremely stable high-energy phosphate compound by muscle, heart, and brain of animals fed the creatine analog, 1-carboxyethyl-2-iminoimidazolidine (homocyclocreatine…
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