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- Publications
- Influence
NF-kappaB functions as a tumour promoter in inflammation-associated cancer.
- E. Pikarsky, R. Porat, +7 authors Y. Ben-Neriah
- Medicine
- Nature
- 2004
The causes of sporadic human cancer are seldom recognized, but it is estimated that carcinogen exposure and chronic inflammation are two important underlying conditions for tumour development, the… Expand
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
- P. Carmeliet, Y. Dor, +13 authors E. Keshet
- Biology, Medicine
- Nature
- 30 July 1998
As a result of deprivation of oxygen (hypoxia) and nutrients, the growth and viability of cells is reduced. Hypoxia-inducible factor(HIF)-1α helps to restore oxygen homeostasis by inducing… Expand
NF-κB functions as a tumour promoter in inflammation-associated cancer
- E. Pikarsky, R. Porat, +7 authors Y. Ben-Neriah
- Biology
- Nature
- 23 September 2004
The causes of sporadic human cancer are seldom recognized, but it is estimated that carcinogen exposure and chronic inflammation are two important underlying conditions for tumour development, the… Expand
VEGF-Induced Adult Neovascularization: Recruitment, Retention, and Role of Accessory Cells
- M. Grunewald, I. Avraham, +7 authors E. Keshet
- Cell
- 2006
Role of HIF-1 alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis (vol 394, pg 485, 1998)
- P. Carmeliet, Y. Dor, +13 authors E. Keshert
- Medicine
- 1 October 1998
- 652
- 24
VEGF-Induced Adult Neovascularization: Recruitment, Retention, and Role of Accessory Cells
- M. Grunewald, I. Avraham, +7 authors E. Keshet
- Biology, Medicine
- Cell
- 13 January 2006
Adult neovascularization relies on the recruitment of circulating cells, but their angiogenic roles and recruitment mechanisms are unclear. We show that the endothelial growth factor VEGF is… Expand
Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis
- M. Darash-Yahana, E. Pikarsky, +8 authors A. Peled
- Medicine
- FASEB journal : official publication of the…
- 1 August 2004
Hormone refractory metastatic prostate cancer remains an incurable disease. We found that high expression levels of the chemokine receptor CXCR4 correlated with the presence of metastatic disease in… Expand
Conditional switching of VEGF provides new insights into adult neovascularization and pro‐angiogenic therapy
To gain insight into neovascularization of adult organs and to uncover inherent obstacles in vascular endothelial growth factor (VEGF)‐based therapeutic angiogenesis, a transgenic system for… Expand
correction: Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
- P. Carmeliet, Y. Dor, +13 authors E. Keshert
- Chemistry
- Nature
- 1 October 1998
This corrects the article DOI: 10.1038/28867
Mutant KRAS is a druggable target for pancreatic cancer
- Elina Zorde Khvalevsky, R. Gabai, +22 authors E. Galun
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 2 December 2013
Significance Pancreatic cancer is still one of the major challenges in clinical oncology. Mutant KRAS is a driving oncogene in the majority of human pancreatic cancer cases. We have made an effort to… Expand