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cyclic nucleotide-gated mechanosensitive ion channel activity

Known as: cyclic nucleotide regulated mechanosensitive ion channel, MscS, cyclic nucleotide gated mechanosensitive ion channel activity 
Enables the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress and when a cyclic nucleotide has been bound… 
National Institutes of Health

Papers overview

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Highly Cited
2019
Highly Cited
2019
A Biomimetic Hierarchical Nanointerface Orchestrates Macrophage Polarization and Mesenchymal Stem Cell Recruitment To Promote Endogenous Bone Regeneration.
The host immune response to bone biomaterials is vital in determining scaffold fates and bone regeneration outcomes. The… 
Highly Cited
2013
Highly Cited
2013
The guidance of stem cell differentiation by substrate alignment and mechanical stimulation.
Highly Cited
2012
Highly Cited
2012
Trophic effects of mesenchymal stem cells in chondrocyte co-cultures are independent of culture conditions and cell sources.
Earlier, we have shown that the increased cartilage production in pellet co-cultures of chondrocytes and bone marrow-derived… 
Highly Cited
2012
Highly Cited
2012
The electrical stimulation of carbon nanotubes to provide a cardiomimetic cue to MSCs.
Highly Cited
2012
Highly Cited
2012
Tenogenic differentiation of human MSCs induced by the topography of electrochemically aligned collagen threads.
Review
2011
Review
2011
The Origins of Mesenchymal Stromal Cell Heterogeneity
Cultured mesenchymal stromal cell (MSC) populations are best characterized by the capacity of some cells within this population… 
Highly Cited
2010
Highly Cited
2010
Age-related molecular genetic changes of murine bone marrow mesenchymal stem cells
BackgroundMesenchymal stem cells (MSC) are pluripotent cells, present in the bone marrow and other tissues that can differentiate… 
Highly Cited
2005
Highly Cited
2005
Pivotal role of the glycine-rich TM3 helix in gating the MscS mechanosensitive channel
The crystal structure of an open form of the Escherichia coli MscS mechanosensitive channel was recently solved. However, the… 
Highly Cited
2005
Highly Cited
2005
The “Dashpot” Mechanism of Stretch-dependent Gating in MscS
The crystal structure of the small conductance mechanosensitive channel (MscS) has been an invaluable tool in the search for the… 
Highly Cited
2004
Highly Cited
2004
Molecular dynamics study of gating in the mechanosensitive channel of small conductance MscS.
Mechanosensitive channels are a class of ubiquitous membrane proteins gated by mechanical strain in the cellular membrane. MscS… 
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