The guidance of stem cell differentiation by substrate alignment and mechanical stimulation.

@article{Subramony2013TheGO,
  title={The guidance of stem cell differentiation by substrate alignment and mechanical stimulation.},
  author={Siddarth D. Subramony and Booth R Dargis and Mario Morales Castillo and Evren U. Azeloglu and Michael S Tracey and Amanda Su and H. H. Lu},
  journal={Biomaterials},
  year={2013},
  volume={34 8},
  pages={1942-53}
}
Mesenchymal stem cells (MSC) represent a promising and clinically relevant cell source for tissue engineering applications. As such, guiding MSCs toward specific lineages and maintaining these phenotypes have been particularly challenging as the contributions of mechanical, chemical and structural cues to the complex differentiation process are largely unknown. To fully harness the potential of MSCs for regenerative medicine, a systematic investigation into the individual and combined effects… CONTINUE READING
42 Citations
63 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 42 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 63 references

Similar Papers

Loading similar papers…