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cullin-RING ubiquitin ligase complex

Known as: cullin complex location, CRL complex location, cullin-RING ubiquitin ligase complex location 
Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated… 
National Institutes of Health

Related topics

Related topics

1 relation
SCF ubiquitin ligase complex

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Oncogenic role of MIR516A in human bladder cancer was mediated by its attenuating PHLPP2 expression and BECN1-dependent autophagy
ABSTRACT Although MIR516A has been reported to be downregulated and act as a tumor suppressor in multiple cancers, its expression… 
2018
2018
High Expressions of CUL4A and TP53 in Colorectal Cancer Predict Poor Survival
Background/Aims: Cullin 4A (CUL4A) is vital in cell survival, development, growth and cell cycle, it plays an important role in… 
2018
2018
MicroRNA-133b inhibits cell proliferation and promotes apoptosis by targeting cullin 4B in esophageal squamous cell carcinoma
microRNAs (miRs) serve a role as modulators during carcinogenesis. It has been demonstrated that the expression of miR-133b is… 
2016
2016
Aiolos collaborates with Blimp-1 to regulate the survival of multiple myeloma cells
The transcriptional repressor B lymphocyte-induced maturation protein-1 (Blimp-1) has crucial roles in the control of plasma cell… 
Highly Cited
2012
Highly Cited
2012
Decline in DJ-1 and decreased nuclear translocation of Nrf2 in Fuchs endothelial corneal dystrophy.
PURPOSE This study sought to determine factors involved in nuclear factor erythroid 2-related factor 2 (Nrf2) regulation and… 
Highly Cited
2006
Highly Cited
2006
A Zinc-binding Region in Vif Binds Cul5 and Determines Cullin Selection*
Human immunodeficiency virus-1 (HIV-1) Vif overcomes the anti-viral activity of APOBEC3G by targeting it for ubiquitination via a… 
Highly Cited
2005
Highly Cited
2005
Tumor-prone phenotype of the DDB2-deficient mice
DDB2 is an essential subunit of the damaged-DNA recognition factor DDB, which is involved in global genomic repair in human cells… 
Highly Cited
2005
Highly Cited
2005
DDB2, the xeroderma pigmentosum group E gene product, is directly ubiquitylated by Cullin 4A-based ubiquitin ligase complex.
2004
2004
Potential effects of tetrodotoxin exposure to human glial cells postulated using microarray approach.
2004
2004
Cul 4 A Physically Associates with MDM 2 and Participates in the Proteolysis of p 53
The cullin 4A (Cul4A) gene is amplified and overexpressed in breast and hepatocellular carcinomas. Cul4A functions as an E3… 
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