Skip to search formSkip to main contentSkip to account menu

cullin-RING ubiquitin ligase complex

Known as: cullin complex location, CRL complex location, cullin-RING ubiquitin ligase complex location 
Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated… 
National Institutes of Health

Related topics

Related topics

1 relation
SCF ubiquitin ligase complex

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
CENP-A Ubiquitylation Contributes to Maintaining the Chromosomal Location of the Centromere
The centromere plays an essential role in accurate chromosome segregation, and the chromosomal location of the centromere is… 
2018
2018
MicroRNA-133b inhibits cell proliferation and promotes apoptosis by targeting cullin 4B in esophageal squamous cell carcinoma
microRNAs (miRs) serve a role as modulators during carcinogenesis. It has been demonstrated that the expression of miR-133b is… 
2017
2017
Cullin 4A is associated with epithelial to mesenchymal transition and poor prognosis in perihilar cholangiocarcinoma
AIM To explore the functional role of cullin 4A (CUL4A), a core subunit of E3 ubiquitin ligase, in perihilar cholangiocarcinoma… 
2017
2017
CUL4A as a marker and potential therapeutic target in multiple myeloma
Multiple myeloma is the most common cause of death of hematological malignancy worldwide. Cullin 4A has been proposed as oncogene… 
2017
2017
Cul4B is a novel prognostic marker in cholangiocarcinoma
Cullin 4B (Cul4B), a scaffold protein that assembles the ubiquitin ligase complex, is involved in a wide variety of physiological… 
2017
2017
Deneddylase 1 regulates deneddylase activity of the Cop9 signalosome in Drosophila melanogaster
NEDD8 conjugation of Cullin has an important role in ubiquitin‐mediated protein degradation. The COP9 signalosome, of which CSN5… 
2015
2015
RETRACTED ARTICLE: Clinical significance of CUL4A in human prostate cancer
Aberrant expression of the Cullin 4A (CUL4A) is found in many tumor types, but the functions and mechanism of CUL4A in prostate… 
Review
2012
Review
2012
The key role of ubiquitination and sumoylation in signaling and cancer: a research topic
Ubiquitination and sumoylation are two important post-translational modifications that play pivotal roles in signaling regulation… 
Highly Cited
2005
Highly Cited
2005
DDB2, the xeroderma pigmentosum group E gene product, is directly ubiquitylated by Cullin 4A-based ubiquitin ligase complex.
2004
2004
Cul 4 A Physically Associates with MDM 2 and Participates in the Proteolysis of p 53
The cullin 4A (Cul4A) gene is amplified and overexpressed in breast and hepatocellular carcinomas. Cul4A functions as an E3… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)