FAQ

cullin-RING ubiquitin ligase complex

Known as: cullin complex location, CRL complex location, cullin-RING ubiquitin ligase complex location 
Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated… (More)

Topic mentions per year

Topic mentions per year

2005-2017
02420052017

Related topics

Related topics

1 relation
SCF ubiquitin ligase complex

Related mentions per year

Related mentions per year

1997-2018
1990200020102020
cullin-RING ubiquitin ligase complex
SCF ubiquitin ligase complex

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity.
HIV-1 encodes the accessory protein Vif, which hijacks a host Cullin-RING ubiquitin ligase (CRL) complex as well as the non… (More)
Is this relevant?
2015
2015
HIV-1 Vpu utilizes both cullin-RING ligase (CRL) dependent and independent mechanisms to downmodulate host proteins
Hijacking of the cullin-RING E3 ubiquitin ligase (CRL) machinery is a common mechanism employed by diverse groups of viruses for… (More)
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2013
2013
Multimeric Complexes among Ankyrin-Repeat and SOCS-box Protein 9 (ASB9), ElonginBC, and Cullin 5: Insights into the Structure and Assembly of ECS-type Cullin-RING E3 Ubiquitin Ligases
Proteins of the ankyrin-repeat and SOCS-box (ASB) family act as the substrate-recognition subunits of ECS-type (ElonginBC-Cullin… (More)
Is this relevant?
2012
2012
Herpes virus deneddylases interrupt the cullin-RING ligase neddylation cycle by inhibiting the binding of CAND1.
The conserved N-terminal domains of the major tegument proteins of herpes viridae encode cysteine proteases with potent ubiquitin… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2011
Review
2011
The cullin protein family
Cullin proteins are molecular scaffolds that have crucial roles in the post-translational modification of cellular proteins… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Dynamics of Cullin-RING Ubiquitin Ligase Network Revealed by Systematic Quantitative Proteomics
Dynamic reorganization of signaling systems frequently accompanies pathway perturbations, yet quantitative studies of network… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2010
Review
2010
Control of cullin-ring ubiquitin ligase activity by nedd8.
The Cullin-RING ubiquitin ligase (CRL) family, which may number as many as 350 different enzymes, has an enormous impact on… (More)
Is this relevant?
2010
2010
Rbx1 flexible linker facilitates cullin-RING ligase function before neddylation and after deneddylation.
In ubiquitination, cullin-RING E3 ubiquitin ligases (CRLs) assist in ubiquitin transfer from ubiquitin-conjugating enzyme E2 to… (More)
Is this relevant?
2009
2009
F-box-directed CRL complex assembly and regulation by the CSN and CAND1.
The COP9 signalosome (CSN) is thought to maintain the stability of cullin-RING ubiquitin ligases (CRL) by limiting the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2008
Review
2008
Cullin-RING ubiquitin ligases: global regulation and activation cycles
Cullin-RING ubiquitin ligases (CRLs) comprise the largest known category of ubiquitin ligases. CRLs regulate an extensive number… (More)
  • figure 1
Is this relevant?