SCF ubiquitin ligase complex

Known as: Skp1/Cul1/F-box protein complex location, SCF ubiquitin ligase complex location, Cul1-RING ubiquitin ligase complex 
A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is… (More)

Topic mentions per year

Topic mentions per year

1997-2017
0102019972017

Papers overview

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Highly Cited
2004
Highly Cited
2004
During synapse formation, specialized subcellular structures develop at synaptic junctions in a tightly regulated fashion. Cross… (More)
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Highly Cited
2003
Highly Cited
2003
Programmed destruction of regulatory proteins through the ubiquitin-proteasome system is a widely used mechanism for controlling… (More)
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Highly Cited
2002
Highly Cited
2002
SCF complexes are the largest family of E3 ubiquitin-protein ligases and mediate the ubiquitination of diverse regulatory and… (More)
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Highly Cited
2002
Highly Cited
2002
Jasmonates (JAs) regulate Arabidopsis thaliana wound and defence responses, pollen development, and stress-related growth… (More)
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Highly Cited
2002
Highly Cited
2002
The SCF ubiquitin E3 ligase regulates ubiquitin-dependent proteolysis of many regulatory proteins such as p27(Kip1), IkappaB, and… (More)
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Highly Cited
2002
Highly Cited
2002
The covalent attachment of ubiquitin is an important determinant for selective protein degradation by the 26S proteasome in… (More)
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Highly Cited
2001
Highly Cited
2001
NEDD8/Rub1 is a ubiquitin (Ub)-like post-translational modifier that is covalently linked to cullin (Cul)-family proteins in a… (More)
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Highly Cited
1999
Highly Cited
1999
We have identified SGT1 as a dosage suppressor of skp1-4, a mutation causing defects in yeast kinetochore function. Sgt1p… (More)
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Highly Cited
1999
Highly Cited
1999
Ubiquitin-mediated proteolysis has a central role in controlling the intracellular levels of several important regulatory… (More)
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Highly Cited
1997
Highly Cited
1997
We have reconstituted the ubiquitination pathway for the Cdk inhibitor Sic1 using recombinant proteins. Skp1, Cdc53, and the F… (More)
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