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SCF ubiquitin ligase complex

Known as: Skp1/Cul1/F-box protein complex location, SCF ubiquitin ligase complex location, Cul1-RING ubiquitin ligase complex 
A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is… (More)

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Topic mentions per year

1997-2017
0102019972017

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Related topics

1 relation
cullin-RING ubiquitin ligase complex

Related mentions per year

Related mentions per year

1997-2018
1990200020102020
SCF ubiquitin ligase complex
cullin-RING ubiquitin ligase complex

Papers overview

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Highly Cited
2004
Highly Cited
2004
An SCF-like ubiquitin ligase complex that controls presynaptic differentiation.
During synapse formation, specialized subcellular structures develop at synaptic junctions in a tightly regulated fashion. Cross… (More)
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Highly Cited
2003
Highly Cited
2003
BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3.
Programmed destruction of regulatory proteins through the ubiquitin-proteasome system is a widely used mechanism for controlling… (More)
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Highly Cited
2002
Highly Cited
2002
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
SCF complexes are the largest family of E3 ubiquitin-protein ligases and mediate the ubiquitination of diverse regulatory and… (More)
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Highly Cited
2002
Highly Cited
2002
COI1 links jasmonate signalling and fertility to the SCF ubiquitin-ligase complex in Arabidopsis.
Jasmonates (JAs) regulate Arabidopsis thaliana wound and defence responses, pollen development, and stress-related growth… (More)
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Highly Cited
2002
Highly Cited
2002
CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex.
The SCF ubiquitin E3 ligase regulates ubiquitin-dependent proteolysis of many regulatory proteins such as p27(Kip1), IkappaB, and… (More)
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Highly Cited
2002
Highly Cited
2002
The F-box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis.
The covalent attachment of ubiquitin is an important determinant for selective protein degradation by the 26S proteasome in… (More)
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Highly Cited
2001
Highly Cited
2001
NEDD8 recruits E2-ubiquitin to SCF E3 ligase.
NEDD8/Rub1 is a ubiquitin (Ub)-like post-translational modifier that is covalently linked to cullin (Cul)-family proteins in a… (More)
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Highly Cited
1999
Highly Cited
1999
SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex.
We have identified SGT1 as a dosage suppressor of skp1-4, a mutation causing defects in yeast kinetochore function. Sgt1p… (More)
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Highly Cited
1999
Highly Cited
1999
The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro.
Ubiquitin-mediated proteolysis has a central role in controlling the intracellular levels of several important regulatory… (More)
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Highly Cited
1997
Highly Cited
1997
F-Box Proteins Are Receptors that Recruit Phosphorylated Substrates to the SCF Ubiquitin-Ligase Complex
We have reconstituted the ubiquitination pathway for the Cdk inhibitor Sic1 using recombinant proteins. Skp1, Cdc53, and the F… (More)
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